Evidence map›Paper›PMID 36106027›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Shipi Shugan Decoction Protected against Sequela of Pelvic Inflammatory Disease via Inhibiting SIRT1/NLRP3 Signaling Pathway in Pelvic Inflammatory Disease Rats.

Yan Wang, Yefang Huang, Ling Shi, Li Huang, Yi Wen, Yihong Cao, Zi Yang, Qian Liu, Xiaolan Yin, Xiaoli Ji

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yan WangDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.ORCID https://orcid.org/0000-0002-8606-0551
Yefang HuangDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.ORCID https://orcid.org/0000-0001-5486-4451
Ling ShiDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.ORCID https://orcid.org/0000-0003-1549-0754
Li HuangDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.ORCID https://orcid.org/0000-0002-2665-3558
Yi WenDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.ORCID https://orcid.org/0000-0003-0384-8747
Yihong CaoDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.ORCID https://orcid.org/0000-0002-3346-8713
Zi YangDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.ORCID https://orcid.org/0000-0002-2813-9587
Qian LiuDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.ORCID https://orcid.org/0000-0003-3255-9928
Xiaolan YinDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.ORCID https://orcid.org/0000-0003-1537-0963
Xiaoli JiDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.ORCID https://orcid.org/0000-0002-7699-3999
Chengdu University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sequela of pelvic inflammatory disease (SPID) is a common and frequently occurring disease clinically. Traditional Chinese medicine (TCM) provided unique advantages in the treatment of SPID. In this study, we aimed to investigate the protective mechanism of Shipi Shugan Decoction (SSD), a Chinese herbal formula, on SPID using a SPID rat model. Mixed bacterial infection and mechanical injury were used for modeling. The chemical composition of SSD was analyzed by ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). The inflammatory factors were detected by enzyme-linked immunosorbent assay (ELISA) and western blot techniques. We found that SSD dose-dependently inhibited the content of IL-18, IL-1

Identifiers

PMID36106027
PMCPMC9467799
OpenAlexW4294959671

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.