Evidence map›Paper›PMID 36105951›Full record

ReviewRSC advances2022

The methodology for preparing domperidone: strategies, routes and reaction processes.

Lili Yu, Rixin Shao, Qingxiang Guo, Hailong Hong, Ning Zhu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lili YuCollege of Chemical Engineering, Inner Mongolia University of Technology Hohhot 010051 China guoqingxiang@imut.edu.cn zhuning@imut.edu.cn.
Rixin ShaoCollege of Chemical Engineering, Inner Mongolia University of Technology Hohhot 010051 China guoqingxiang@imut.edu.cn zhuning@imut.edu.cn.
Qingxiang GuoCollege of Chemical Engineering, Inner Mongolia University of Technology Hohhot 010051 China guoqingxiang@imut.edu.cn zhuning@imut.edu.cn.
Hailong HongCollege of Chemical Engineering, Inner Mongolia University of Technology Hohhot 010051 China guoqingxiang@imut.edu.cn zhuning@imut.edu.cn.ORCID https://orcid.org/0000-0002-7533-4115
Ning ZhuCollege of Chemical Engineering, Inner Mongolia University of Technology Hohhot 010051 China guoqingxiang@imut.edu.cn zhuning@imut.edu.cn.ORCID https://orcid.org/0000-0002-7535-1310

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Domperidone is a powerful peripheral dopamine receptor antagonist; however, a systematic review of the synthetic methods and processes of this drug has not been reported so far. This review summarizes the synthetic strategies, synthetic routes and reaction processes of domperidone in detail. Domperidone can be synthesized from the coupling reaction of two benzimidazolone derivatives (intermediates 1 and 2). Intermediate 1 can be prepared by two synthetic routes: the cyclization of

Identifiers

PMID36105951
PMCPMC9377158

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.