Evidence map›Paper›PMID 36105843›Full record

ArticleRadiology case reports2022

Superficial intraventricular surface siderosis brain.

Edlira Harizi, Kledisa Shemsi, Ilir Ahmetgjekaj, Anusha Parisapogu, Keti Mamillo, Fjolla Hyseni, Simmy Lahori, Kampa Prathima, Chandalji Naik Banavath, Zaina Syed and 6 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Radiology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 5 countries.

Edlira HariziDepartment of Neurology, Regional Hospital Durres, Albania.
Kledisa ShemsiRegional Hospital Durres, Tirana, Albania.
Ilir AhmetgjekajUniversity Clinical Center, Clinic of Radiology, Pristina, Kosovo.
Anusha ParisapoguDepartment of Infectious Diseases, Mayo Clinic, Rochester, NY, USA.
Keti MamilloDepartment of Anesthesiology, University Medical Center of Tirana "Mother Teresa", Tirana, Albania.
Fjolla HyseniDepartment of Pediatrics, NYU Langone Health, New York, NY, USA.
Simmy LahoriDepartment of Radiology, Mayo Clinic, Rochester, NY, USA.
Kampa PrathimaLifetime Wellness Rx International Ltd, Bengaluru, India.
Chandalji Naik BanavathGuntur Medical College, Andhra Pradesh, India.
Zaina SyedBiochemistry, Hunter College CUNY, New York, NY, USA.
Srikrishnan PichuthirumalaiSakra World Hospital, Bengaluru, India.
Juna MusaDepartment of Endocrinology, Diabetes and Nutrition, Mayo Clinic, Rochester, NY, USA.
Jasmine SainiDepartment of Endocrinology, Mayo Clinic, Rochester, NY, USA.
Arieta Hasani AlidemaUniversity for Business and Technology (UBT), Pristina, Kosovo.
Valon VokshiDepartment of Anesthesiology, University Clinical Center of Kosovo, Pristina, Kosovo.
Mohammad Abubaker SiddiqueNorth East Medical College & Hospital, Sylhet, Bangladesh.
Mayo Clinic · USAleksandër Moisiu University · ALUniversity Clinical Center of Kosovo · XKGuntur Medical College · INHunter College · USMayo Clinic in Florida · USMother Teresa Hospital · ALNorth East University · BDNYU Langone Health · USUniversity for Business and Technology · XK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Superficial siderosis of the central nervous system is a chronic condition characterized by hemosiderin deposition in the brain and spinal cord. It's diagnosed by brain MRI. It can be caused by low-grade extravasation of blood into the subarachnoid space of the brain. There are 2 types of superficial siderosis cortical and infratentorial. Although asymptomatic in many cases; Cerebellar-predominant siderosis, a subtype of infratentorial, can affect hearing, gait, and even muscles. In this report, we present a case of a 51-year old female with complaints of hearing loss, unsteadiness in his lower limb, and spastic paresis. During MRI neuroimaging, we noticed findings of hypointensity areas within the brainstem and cerebellum, probably due to hemosiderin deposition. Based on the MRI findings, the patient was diagnosed with superficial siderosis. The patient was started on deferiprone and followed for the consecutive 18 months. Moderate improvement of the hearing loss and ataxia was noted while no change in muscle force. However, the repetitive MRI did not reveal any changes compared to the previous one.

Identifiers

PMID36105843
PMCPMC9464766
OpenAlexW4294795222

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.