Evidence map›Paper›PMID 36105786›Full record

ArticleInternational journal of clinical practice2022

Peach Kernel Extracts Inhibit Lipopolysaccharide-Induced Activation of HSC-T6 Hepatic Stellate Cells.

Hong-Jie Chen, Jin-Yuan Huang, Chih-Yuan Ko

Open access · goldAbstract read
In one paragraph

Article in International journal of clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Hong-Jie ChenDepartment of Clinical Nutrition, People's Hospital of Leshan, Leshan 614000, China.ORCID https://orcid.org/0000-0002-5922-7977
Jin-Yuan HuangDepartment of Clinical Nutrition, Suzhou Dushu Lake Hospital, Suzhou 215123, Jiangsu, China.
Chih-Yuan KoDepartment of Clinical Nutrition, The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China.ORCID https://orcid.org/0000-0002-5767-3041
Fujian Medical University · CNLeshan Normal University · CNThe Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an important role for hepatic stellate cells (HSCs) in liver fibrosis. As it stands, many traditional Chinese medicine formulations can effectively improve liver fibrosis, whether it is clinically used or in animal studies; however, the efficacy and mechanism of the main formulations remain unclear, including the peach kernel, which contains numerous phytochemicals with a wide range of biological activities. The purpose of this study was to investigate peach kernel's anti-liver fibrosis effects. In this study, peach kernel extracts inhibited lipopolysaccharide (LPS) activation in HSC-T6 cells and the expression of

Indexed as

Hepatic Stellate CellsPrunus persicaAnimalsCell LineHumansLipopolysaccharidesLiver CirrhosisLipopolysaccharides

Identifiers

PMID36105786
PMCPMC9444415
OpenAlexW4293769244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.