Evidence map›Paper›PMID 36105674›Full record

ReviewMaterials today. Bio2022

Roles and current applications of S-nitrosoglutathione in anti-infective biomaterials.

Hu Qian, Zhimin Ye, Lanping Pi, Jun Ao

Open access · goldAbstract readReview
In one paragraph

Review in Materials today. Bio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Nitric Oxide-ReleasingPharmaceutics · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hu QianDepartment of Orthopaedic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Zhimin YeDepartment of Pathology, School of Basic Medical Sciences, Central South University, Changsha, China.
Lanping PiNursing Department, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Jun AoDepartment of Orthopaedic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Zunyi Medical University · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial infections can compromise the physical and biological functionalities of humans and pose a huge economical and psychological burden on infected patients. Nitric oxide (NO) is a broad-spectrum antimicrobial agent, whose mechanism of action is not affected by bacterial resistance. S-nitrosoglutathione (GSNO), an endogenous donor and carrier of NO, has gained increasing attention because of its potent antibacterial activity and efficient biocompatibility. Significant breakthroughs have been made in the application of GSNO in biomaterials. This review is based on the existing evidence that comprehensively summarizes the progress of antimicrobial GSNO applications focusing on their anti-infective performance, underlying antibacterial mechanisms, and application in anti-infective biomaterials. We provide an accurate overview of the roles and applications of GSNO in antibacterial biomaterials and shed new light on the avenues for future studies.

Indexed as

A.baumannii, Acinetobacter baumanniiAgNPs, Silver nanoparticlesAntibacterial propertyBacterial resistanceBiomaterialsBMSCs, Bone marrow stem cellsC.albicans, Candida albicanscftr, cystic fibrosis transmembrane conductance regulatory geneCS/GE, Chitosan/gelatinCu, copperd, dayDMSO, Dimethyl sulfoxideDPA, Diethylenetriamine pentaacetic acidECC, Extracorporeal circulationECM, Experimental cerebral malariaE. coli, Escherichia coliE.tenella, Eimeria tenellaGSNOR, S-Nitrosoglutathione ReductaseGSNO, S-NitrosoglutathioneHCC, Human cervical carcinomaHDFs, Human dermal fibroblastsh, hourH.pylori, Helicobacter pyloriHUVEC, Human umbilical vein endothelial cellsICR, Imprinted control regionInfectionK.Pneumonia, Klebsiella PneumoniaL.amazonensis, Leishmania amazonensisL.major, Leishmania majormin, minuteMOF, Metal–organic frameworkMRPA, Multidrug-resistant Pseudomonas aeruginosaMRSA, Methicillin resistant Staphylococcus aureusM.smegmatis, Mycobacterium smegmatisM.Tuberculosis, Mycobacterium tuberculosisNA, Not availableN. gonorrhoeae, Neisseria gonorrhoeaeN.meningitidis, Neisseria meningitidisNO-np, NO-releasing nanoparticulate platformNP, NanoparticleP.aeruginosa, Pseudomonas aeruginosaP.berghei, Plasmodium bergheiPCL, PolycaprolactonePCVAD, Porcine circovirus-associated diseasePDA-GSNO NPs, Polydopamine nanoparticles containing GSNOPDAM@Cu, polydopamine based copper coatingsPEG, polyethylene glycolPHB, polyhydroxybutyratePLA, polylactic acidPLGA, poly(lactic-co-glycolic acid)P.mirabilis, Proteus mirabilispSiNPs, porous silicon nanoparticlesPTT, Photothermal therapyPVA/PEG, poly(vinyl alcohol)/poly(ethylene glycol)PVA, poly(vinyl alcohol)PVC, poly(vinyl chloride)SAKI, Septic acute kidney injuryS.aureus, Staphylococcus aureusSCI, Spinal cord slicesS.epidermidis, Staphylococcus epidermidisSe, SeleniumS-nitrosoglutathioneSp3, Specificity proteins 3S.pneumoniae, Streptococcus pneumoniaeS. typhimurium, Salmonella typhimuriumTDC, Tunneled dialysis cathetersTMOS, Tetramethylorthosilicatew, weekZnO, Zinc oxide

Identifiers

PMID36105674
PMCPMC9465324
OpenAlexW4294676428

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.