Evidence map›Paper›PMID 36105416›Full record

ArticleBJR open2022

Salvaging low contrast abdominal CT studies using noise-optimised virtual monoenergetic image reconstruction.

Scherwin Mahmoudi, Marvin Lange, Lukas Lenga, Ibrahim Yel, Vitali Koch, Christian Booz, Simon Martin, Simon Bernatz, Thomas Vogl, Moritz Albrecht and 1 more

Abstract read
In one paragraph

Article in BJR open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Scherwin MahmoudiDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai, Frankfurt, Germany.ORCID https://orcid.org/0000-0002-4020-1873
Marvin LangeDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai, Frankfurt, Germany.
Lukas LengaDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai, Frankfurt, Germany.
Ibrahim YelDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai, Frankfurt, Germany.
Vitali KochDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai, Frankfurt, Germany.
Christian BoozDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai, Frankfurt, Germany.
Simon MartinDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai, Frankfurt, Germany.
Simon BernatzDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai, Frankfurt, Germany.
Thomas VoglDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai, Frankfurt, Germany.
Moritz AlbrechtDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai, Frankfurt, Germany.
Jan-Erik ScholtzDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai, Frankfurt, Germany.ORCID https://orcid.org/0000-0003-4631-6126

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To assess the impact of noise-optimised virtual monoenergetic imaging (VMI+) on image quality and diagnostic evaluation in abdominal dual-energy CT scans with impaired portal-venous contrast. Methods: We screened 11,746 patients who underwent portal-venous abdominal dual-energy CT for cancer staging between 08/2014 and 11/2019 and identified those with poor portal-venous contrast.Standard linearly-blended image series and VMI+ image series at 40, 50, and 60 keV were reconstructed. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of abdominal organs and vascular structures were calculated. Image noise, image contrast and overall image quality were rated by three radiologists using 5-point Likert scale. Results: 452 of 11,746 (4%) exams were poorly opacified. We excluded 190 cases due to incomplete datasets or multiple exams of the same patient with a final study group of 262. Highest CNR values in all abdominal organs (liver, 6.4 ± 3.0; kidney, 17.4 ± 7.5; spleen, 8.0 ± 3.5) and vascular structures (aorta, 16.0 ± 7.3; intrahepatic vein, 11.3 ± 4.7; portal vein, 15.5 ± 6.7) were measured at 40 keV VMI+ with significantly superior values compared to all other series. In subjective analysis, highest image contrast was seen at 40 keV VMI+ (4.8 ± 0.4), whereas overall image quality peaked at 50 keV VMI+ (4.2 ± 0.5) with significantly superior results compared to all other series ( Conclusions: Image reconstruction using VMI+ algorithm at 50 keV significantly improves image contrast and image quality of originally poorly opacified abdominal CT scans and reduces the number of non-diagnostic scans. Advances in knowledge: We validated the impact of VMI+ reconstructions in poorly attenuated DECT studies of the abdomen in a big data cohort.

Identifiers

PMID36105416
PMCPMC9446156

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.