ArticleFrontiers in physiology2022
Exposure to dim light at night alters daily rhythms of glucose and lipid metabolism in rats.
Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 34 citations in OpenAlex.
- Chronic exposure to artificial light at night dampens rhythms in locomotor activity, metabolism, and sleep in female mice.Physiology & behavior · 2026Article
- Exposure to Dim Light at Night Impairs Photoperiodic and Metabolic Gene Expression in Syrian Hamsters (Mesocricetus auratus).Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026Article
- Restoration of circadian rhythm as novel targets against sarcopenia.Chinese medical journal · 2026Review
- Article
- Obesity mediates the association of outdoor artificial light at night with type 2 diabetes mellitus.iScience · 2026Article
- Exogenous melatonin alleviates abnormal glucose metabolism in the breast muscle under long-term light exposure through the parasympathetic pathway.Journal of advanced research · 2026Article
- Influence of Artificial Light at Night on Thyroid Gland Histology inAnimals : an open access journal from MDPI · 2026Article
- Chronopharmacology-Driven Precision Therapies for Time-Optimized Cardiometabolic Disease Management.Biology · 2026Review
- Dim light at night alters photoperiodic perception in male Syrian hamsters (Mesocricetus auratus).Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025Article
- Artificial Light at Night, Sleep Disruption, and Liver Health: Implications for MASLD Pathogenesis.International journal of environmental research and public health · 2025Review
- Dim light at night impacts circadian rhythms and Alzheimer's disease-like neuroinflammation and neuropathology in humanized APP SAA knock-in mice.bioRxiv : the preprint server for biology · 2025Article
- Endocannabinoid signaling is a critical link between circadian desynchronization and metabolic dysfunction.bioRxiv : the preprint server for biology · 2025Article
- Article
- Lipid metabolic adaptations during inflammation are controlled by the circadian clock and impaired by light at night.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025Article
- Circadian phase inversion causes insulin resistance in a rat model of night work and jet lag.Scientific reports · 2025Article
- Partial night lighting may reduce the physiological impact of artificial light at night on captive zebra finches.Frontiers in physiology · 2025Article
- Light pollution disrupts seasonal reproductive phenotypes and reduces lifespan in the West Nile vector, Culex pipiens.Journal of insect physiology · 2024Article
- Effects of exposure to outdoor light at night on blood lipids in China: a nationwide cross-sectional study.Scientific reports · 2024Article
- Effects of Different Photoperiods on Growth Performance, Glucose Metabolism, Acetylcholine, and Its Relative Acetylcholine Receptor Modulation in Broiler Chickens.Animals : an open access journal from MDPI · 2024Article
- Circadian Rhythms of Body Temperature and Locomotor Activity in Spontaneously Hypertensive Rats under Frequent Changes in Light Conditions.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nocturnal light pollution has been rapidly increasing during the last decades and even though dim artificial light at night (ALAN) has been associated with metabolic diseases, its mechanism is still far from clear. Therefore, the aim of our study was to thoroughly analyze the effects of ALAN on energy metabolism, metabolites, metabolic hormones, and gene expression. Male Wistar rats were kept in either the standard light:dark (12:12) cycle or exposed to ALAN (∼2 lx) during the whole 12-h dark phase for 2 weeks. Energy metabolism was measured in metabolic cages. In addition, we measured plasma and hepatic metabolites, clock and metabolic gene expression in the liver and epididymal adipose tissue, and plasma hormone levels. In ALAN rats, we observed an unexpected transitory daytime peak of locomotor activity and a suppression of the peak in locomotor activity at the beginning of the dark period. These changes were mirrored in the respiratory exchange ratio. Plasma metabolites became arrhythmic, and plasma and hepatic cholesterol levels were increased. Lost rhythmicity of metabolites was associated with disrupted behavioral rhythms and expression of metabolic genes. In the liver, the rhythms of metabolic sensors were either phase-advanced (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.