Evidence map›Paper›PMID 36105228›Full record

ArticleFrontiers in pharmacology2022

Inhibition of adenylyl cyclase 1 by ST034307 inhibits IP

Samuel J Bose, Matthew J Read, Emily Akerman, Rebecca A Capel, Thamali Ayagama, Angela Russell, Derek A Terrar, Manuela Zaccolo, Rebecca A B Burton

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Activation of IPAmerican journal of physiology. Heart and circulatory physiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Samuel J BoseDepartment of Pharmacology, University of Oxford, Oxford, United Kingdom.
Matthew J ReadDepartment of Pharmacology, University of Oxford, Oxford, United Kingdom.
Emily AkermanDepartment of Pharmacology, University of Oxford, Oxford, United Kingdom.
Rebecca A CapelDepartment of Pharmacology, University of Oxford, Oxford, United Kingdom.
Thamali AyagamaDepartment of Pharmacology, University of Oxford, Oxford, United Kingdom.
Angela RussellDepartment of Pharmacology, University of Oxford, Oxford, United Kingdom.
Derek A TerrarDepartment of Pharmacology, University of Oxford, Oxford, United Kingdom.
Manuela ZaccoloDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Rebecca A B BurtonDepartment of Pharmacology, University of Oxford, Oxford, United Kingdom.
University of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial arrhythmias, such as atrial fibrillation (AF), are a major mortality risk and a leading cause of stroke. The IP

Indexed as

adenylyl cyclasecalcium signallingcardiac atriacyclic AMPinositol trisphosphatepacemakingsinoatrial node

Identifiers

PMID36105228
PMCPMC9465815
OpenAlexW4293434503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.