Evidence map›Paper›PMID 36105146›Full record

ArticleFrontiers in cellular and infection microbiology2022

Characteristics of salivary microbiota in children with obstructive sleep apnea: A prospective study with polysomnography.

Xin Huang, Xuehui Chen, Xu Gong, Ying Xu, Zhifei Xu, Xuemei Gao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xin HuangDepartment of Orthodontics, Peking University School and Hospital of Stomatology, Beijing, China.
Xuehui ChenDepartment of Orthodontics, Peking University School and Hospital of Stomatology, Beijing, China.
Xu GongDepartment of Orthodontics, Peking University School and Hospital of Stomatology, Beijing, China.
Ying XuDepartment of Orthodontics, Peking University School and Hospital of Stomatology, Beijing, China.
Zhifei XuDepartment of Respiratory Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Xuemei GaoDepartment of Orthodontics, Peking University School and Hospital of Stomatology, Beijing, China.
Peking University · CNBeijing Children’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The present study aimed to investigate the characteristics of salivary microbiota of children with obstructive sleep apnea (OSA) and to assess longitudinal alterations in salivary microbiota before and after adenotonsillectomy. Methods: A set of cross-sectional samples consisted of 36 OSA children (17 boys and 19 girls, 7.47 ± 2.24 years old) and 22 controls (9 boys and 13 girls, 7.55 ± 2.48 years old) were included in the study, among which eight OSA children (five boys and three girls, 8.8 ± 2.0 years old) who underwent treatment of adenotonsillectomy were followed up after 1 year. Saliva samples were collected, and microbial profiles were analyzed by bioinformatics analysis based on 16S rRNA sequencing. Results: In cross-sectional samples, the OSA group had higher α-diversity as estimated by Chao1, Shannon, Simpson, Pielou_e, and observed species as compared with the control group ( Conclusions: A significantly higher microbial diversity and a significant difference in microbial composition and abundance were identified in salivary microbiota of OSA children compared with controls. Meanwhile, some characteristic genera (

Indexed as

MicrobiotaSleep Apnea, ObstructiveChildChild, PreschoolCross-Sectional StudiesFemaleHumansMalePolysomnographyPrevotellaProspective StudiesRNA, Ribosomal, 16SRNA, Ribosomal, 16S16S rRNA gene sequencingadenotonsillectomyPediatric obstructive sleep apneapolysomnographysalivary microbiota

Identifiers

PMID36105146
PMCPMC9465092
OpenAlexW4293531297

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.