Evidence map›Paper›PMID 36105141›Full record

ArticleInternational journal of bioprinting2022

3D-bioprinted Recombination Structure of Hertwig's Epithelial Root Sheath Cells and Dental Papilla Cells for Alveolar Bone Regeneration.

Huilin Tang, Fei Bi, Guoqing Chen, Shuning Zhang, Yibing Huang, Jiahao Chen, Li Xie, Xiangchen Qiao, Weihua Guo

Open access · diamondAbstract read
In one paragraph

Article in International journal of bioprinting, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
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  5. Bioprinting of gelatin-based materials for orthopedic application.Frontiers in bioengineering and biotechnology · 2024
    Review
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Huilin TangState Key Laboratory of Oral Disease, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Fei BiState Key Laboratory of Oral Disease, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Guoqing ChenDepartment of Human Anatomy, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Shuning ZhangState Key Laboratory of Oral Disease, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Yibing HuangState Key Laboratory of Oral Disease, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Jiahao ChenState Key Laboratory of Oral Disease, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Li XieNational Engineering Laboratory for Oral Regenerative Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Xiangchen QiaoChengdu Renjitiancheng Biotechnology Limited Corporation, Chengdu, China.
Weihua GuoState Key Laboratory of Oral Disease, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Sichuan University · CNState Key Laboratory of Oral DiseasesUniversity of Electronic Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional (3D) bioprinting is an emerging method for tissue regeneration. However, promoting the epithelial-mesenchymal interaction (EMI), while maintaining the characteristics of epithelial cells has always been a challenge in tissue engineering. Since EMI acts as a critical factor in bone regeneration, this study aims to promote EMI by recombining epithelial and mesenchymal cells through 3D bioprinting. Hertwig's epithelial root sheath (HERS) is a transient structure appeared in the process of tooth root formation. Its epithelial characteristics are easy to attenuate under appropriate culture environment. We recombined HERS cells and dental papilla cells (DPCs) through 3D bioprinting to simulate the micro-environment of cell-cell interaction

Indexed as

3D bioprintingAlveolar bone regenerationEpithelial-mesenchymal interactionHertwig’s epithelial root sheath cell

Identifiers

PMID36105141
PMCPMC9468846
OpenAlexW4282834444

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.