Evidence map›Paper›PMID 36105101›Full record

ArticleFrontiers in genetics2022

Serum differential proteomic profiling of patients with isolated methylmalonic acidemia by iTRAQ.

Sitao Li, Congcong Shi, Yao Cai, Xia Gu, Hui Xiong, Xiaoyu Liu, Yinchun Zhang, Xin Xiao, Fei Ma, Hu Hao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sitao LiDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat sen University, Guangzhou, China.
Congcong ShiInborn Errors of Metabolism Laboratory, The Sixth Affiliated Hospital, Sun Yat sen University, Guangzhou, China.
Yao CaiDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat sen University, Guangzhou, China.
Xia GuDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat sen University, Guangzhou, China.
Hui XiongDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat sen University, Guangzhou, China.
Xiaoyu LiuDepartment of Child Care, The Maternity and Child Health Care Hospital of Tianhe District, Guangzhou, China.
Yinchun ZhangDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat sen University, Guangzhou, China.
Xin XiaoDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat sen University, Guangzhou, China.
Fei MaInborn Errors of Metabolism Laboratory, The Sixth Affiliated Hospital, Sun Yat sen University, Guangzhou, China.
Hu HaoDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat sen University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isolated methylmalonic acidemia (MMA) is an inherited organic acid metabolic disorder in an autosomal recessive manner, caused by mutations in the methylmalonyl coenzyme A mutase gene, and the isolated MMA patients often suffer from multi-organ damage. The present study aimed to profile the differential proteome of serum between isolated MAA patients and healthy control. The

Indexed as

cholesterol metabolismdifferential proteomeimmunoglobulinsiTRAQmethylmalonic acidemiamethylmalonyl coenzyme A mutase

Identifiers

PMID36105101
PMCPMC9464863

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.