Evidence map›Paper›PMID 36104820›Full record

ArticleTrials2022

Cognitive-motor telerehabilitation in multiple sclerosis (CoMoTeMS): study protocol for a randomised controlled trial.

Delphine Van Laethem, Frederik Van de Steen, Daphne Kos, Maarten Naeyaert, Peter Van Schuerbeek, Miguel D'Haeseleer, Marie B D'Hooghe, Jeroen Van Schependom, Guy Nagels

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05355389 (Cognitive-motor Telerehabilitation in Multiple Sclerosis), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05355389 narecruitingnot on this map

Cognitive-motor Telerehabilitation in Multiple Sclerosis

TypeinterventionalSponsorUniversitair Ziekenhuis BrusselRan2022 to 2027Enrolled90ConditionsMultiple SclerosisArmsCognitive training, Motor training
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Delphine Van LaethemAIMS Lab, Center For Neurosciences, UZ Brussel, Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussel, Belgium. delphine.van.laethem@vub.be.ORCID http://orcid.org/0000-0001-8341-2761
Frederik Van de SteenAIMS Lab, Center For Neurosciences, UZ Brussel, Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussel, Belgium.
Daphne KosDepartment of Rehabilitation, National Multiple Sclerosis Center, Melsbroek, Belgium.
Maarten NaeyaertDepartment of Radiology, UZ Brussel, Brussel, Belgium.
Peter Van SchuerbeekDepartment of Radiology, UZ Brussel, Brussel, Belgium.
Miguel D'HaeseleerNeurology Department, National Multiple Sclerosis Center, Melsbroek, Belgium.
Marie B D'HoogheNeurology Department, National Multiple Sclerosis Center, Melsbroek, Belgium.
Jeroen Van SchependomAIMS Lab, Center For Neurosciences, UZ Brussel, Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussel, Belgium.
Guy NagelsAIMS Lab, Center For Neurosciences, UZ Brussel, Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussel, Belgium.
Vrije Universiteit Brussel · BEEuropean Platform of Women Scientists · BEUniversitair Ziekenhuis Brussel · BE

Funding

Fonds Wetenschappelijk Onderzoek 1267422NFonds Wetenschappelijk Onderzoek 1805620NFonds Wetenschappelijk Onderzoek 1SD5322N
6 · The paper itself

Abstract

backgroundThe management of cognitive impairment is an important goal in the treatment of multiple sclerosis (MS). While cognitive rehabilitation has been proven to be effective in improving cognitive performance in MS, research in the elderly indicates a higher effectiveness of combined cognitive-motor rehabilitation. Here, we present the protocol of a randomised controlled clinical trial to assess whether a combined cognitive-motor telerehabilitation programme is more effective in improving working memory than only cognitive or motor training. METHODS/

designThe CoMoTeMS-trial is a two-centre, randomised, controlled and blinded clinical trial. A total of 90 patients with MS will receive 12 weeks of either a combined cognitive-motor telerehabilitation programme or only cognitive or motor training. The primary outcome is a change in the digit span backwards. Secondary outcomes are other cognitive changes (Brief International Cognitive Assessment for Multiple Sclerosis and Backward Corsi), Expanded Disability Status Scale (EDSS), 6-Min Walk Test, 25-Foot Walk Test, 9-Hole Peg Test, anxiety and depression, fatigue, quality of life, cognitive and physical activity level, electroencephalography and magnetic resonance imaging of the brain. DISCUSSION: We hypothesise that the improvement in digit span backwards after 12 weeks of treatment will be significantly higher in the group treated with the combined cognitive-motor telerehabilitation programme, compared to the groups receiving only cognitive and only motor training.

trial registrationClinicalTrials.gov NCT05355389. Registered on 2 May 2022.

Indexed as

Multiple SclerosisTelerehabilitationAgedCognitionFatigueHumansQuality of LifeRandomized Controlled Trials as TopicCognitionCognitive-motor rehabilitationCognitive rehabilitationMultiple sclerosisRandomised controlled trialRehabilitationTelerehabilitation

Identifiers

PMID36104820
PMCPMC9473474
OpenAlexW4295700828

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.