Trial reportJournal of neuroengineering and rehabilitation2022
Effects of intervention combining transcranial direct current stimulation and foot core exercise on sensorimotor function in foot and static balance.
Trial report in Journal of neuroengineering and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Does transcranial direct current stimulation enhance sensorimotor recovery in chronic ankle instability? A systematic review and meta-analysis.Journal of neuroengineering and rehabilitation · 2026Pooled it
- Acute effects of anodal transcranial direct current stimulation on endurance and maximal voluntary contraction in lower limbs: a systematic review and meta-analysis.Experimental brain research · 2025Pooled it
- Can exercise therapy combined with transcranial direct current stimulation further improve balance ability in individuals with chronic ankle instability? A systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- Effects of physical training combined with transcranial direct current stimulation on maximal strength and lower limb explosive strength in healthy adults.Frontiers in sports and active living · 2024Pooled it
- Trial
- Individualized transcranial direct current stimulation combined with foot core exercise improves foot and ankle sensorimotor function and static postural control in individuals with chronic ankle instability.Journal of neuroengineering and rehabilitation · 2025Trial
- Effects of Different Intervention Methods on Postural Control in Athletes with Chronic Ankle Instability: A Randomized Controlled Trial.Journal of sports science & medicine · 2025Trial
- Functional characteristics in supraspinal networks and sensorimotor function following individualized dose-controlled HD-tDCS during foot core exercise in chronic ankle instability.Journal of sport and health science · 2026Article
- Transcranial electrical stimulation (TES) in human motor Optimization: Mechanisms, safety, and emerging applications.Biochemistry and biophysics reports · 2025Review
- Research progress on transcranial direct current stimulation for improving muscle strength: a narrative review.Frontiers in neurology · 2025Review
- The Effect of Transcranial Direct Current Stimulation on Lower-Limb Endurance Performance: A Systematic Review.Bioengineering (Basel, Switzerland) · 2024Review
- High-Definition Trans-Spinal Current Stimulation Improves Balance and Somatosensory Control: A Randomised, Placebo-Controlled Trial.Biomedicines · 2024Article
- Chronic Functional Adaptations Induced by the Application of Transcranial Direct Current Stimulation Combined with Exercise Programs: A Systematic Review of Randomized Controlled Trials.Journal of clinical medicine · 2023Review
- Effects of tDCS on Foot Biomechanics: A Narrative Review and Clinical Applications.Bioengineering (Basel, Switzerland) · 2023Review
- Effects of high-definition transcranial direct current stimulation on the cortical-muscular functional coupling and muscular activities of ankle dorsi-plantarflexion under running-induced fatigue.Frontiers in physiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to examine the effects of combining transcranial direct current stimulation (tDCS) and foot core exercise (FCE) on the sensorimotor function of the foot (i.e., toe flexor strength and passive ankle kinesthesia) and static balance.
methodsIn this double-blinded and randomized study, 30 participants were randomly assigned into two groups: tDCS combined with FCE and sham combined with FCE (i.e., control group). The participants received 2 mA stimulation for 20 min concurrently with FCE over 4 weeks (i.e., three sessions per week). After the first two groups completed the intervention, a reference group (FCE-only group) was included to further explore the placebo effects of sham by comparing it with the control group. Foot muscle strength, passive ankle kinesthesia, and static balance were assessed at baseline and after the intervention.
resultsCompared with the control group and baseline, tDCS combined with FCE could increase toe flexor strength (p < 0.001) and decrease the passive kinesthesia threshold of ankle eversion (p = 0.002). No significant differences in static balance were observed between tDCS + FCE and control groups. The linear regression models showed an association towards significance between the percent changes in metatarsophalangeal joint flexor strength and the anteroposterior average sway velocity of the center of gravity in one-leg standing with eyes closed following tDCS + FCE (r
conclusionParticipating in 4 weeks of intervention using tDCS in combination with FCE effectively enhances toe flexor strength and foot-ankle sensory function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.