ArticleBMC endocrine disorders2022
Association of sleep duration and insomnia with metabolic syndrome and its components in the Women's Health Initiative.
Article in BMC endocrine disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 16 citations in OpenAlex.
- Assessing Associations Between Environmental, Sleep, and Physical Activity Factors and Metabolic Syndrome Risk: Protocol for the FEASible Study.JMIR research protocols · 2026Article
- The association between sleep duration, insomnia and sleep patterns with metabolic syndrome: an integrative review.Frontiers in clinical diabetes and healthcare · 2026Review
- Article
- Age-Related Differences in Anthropometric and Lifestyle Factors Linked to Metabolic Syndrome in Women with Overweight and Obesity: A Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Associations of Sleep-Disordered Breathing and Insomnia with Incident Metabolic Syndrome - The Hispanic Community Health Study/Study of Latinos.Nature and science of sleep · 2025Article
- Dietary management improves sleep quality in patients with metabolic syndrome: the mediating roles of metabolic, inflammatory, and oxidative stress changes.Frontiers in nutrition · 2025Article
- Association Between Sleep Duration and Related Risk Factors with Metabolic Syndrome: A Systematic Review and Meta-analysis.International journal of preventive medicine · 2025Review
- Physical activity, body weight, and liver function as factors increasing Insomnia index among Korean adults: a cross-sectional analysis.Sleep & breathing = Schlaf & Atmung · 2024Article
- Short sleep duration is associated with higher risk of central obesity in adults: A systematic review and meta-analysis of prospective cohort studies.Obesity science & practice · 2024Review
- Metabolic and vascular imaging markers for investigating Alzheimer's disease complicated by sleep fragmentation in mice.Frontiers in physiology · 2024Article
- Association of insomnia and daytime napping with metabolic syndrome and its components in a Korean population: an analysis of data from the Korean Genome and Epidemiology Study.Epidemiology and health · 2024Article
- Associations between Milk Intake and Sleep Disorders in Chinese Adults: A Cross-Sectional Study.Nutrients · 2023Article
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Authors and funding
13 authors at 9 institutions in 1 country.
Funding
Abstract
backgroundEpidemiological evidence suggests that inadequate sleep duration and insomnia may be associated with increased risk of metabolic syndrome (MetS). However, longitudinal data with repeated measures of sleep duration and insomnia and of MetS are limited. We examined the association of sleep duration and insomnia with MetS and its components using longitudinal data from the Women's Health Initiative (WHI).
methodsThe study included postmenopausal women (ages 50-79 years) diabetes-free at enrollment in the WHI, with baseline data on sleep duration (n = 5,159), insomnia (n = 5,063), MetS, and its components. Repeated measures of self-reported sleep duration and insomnia were available from years 1 or 3 of follow-up and of the MetS components from years 3, 6 and 9. Associations were assessed using logistic regression and generalized estimating equations models, and odds ratios and 95% confidence intervals (CI) adjusted for major risk factors were calculated.
resultsIn cross-sectional analysis, baseline sleep duration ≥ 9 h was positively associated with MetS (OR = 1.51; 95%CI 1.12-2.04), while sleep duration of 8- < 9 h was associated with waist circumference > 88 cm and triglycerides ≥ 150 mg/dL (OR = 1.18; 95%CI 1.01-1.40 and OR = 1.23; 95%CI 1.05-1.46, respectively). Insomnia had a borderline positive association with MetS (OR = 1.14; 95%CI 0.99-1.31), and significant positive associations with waist circumference > 88 cm and glucose ≥ 100 mg/dL (OR = 1.18; 95%CI 1.03-1.34 and OR = 1.17; 95%CI 1.02-1.35, respectively). In the longitudinal analysis, change from restful sleep to insomnia over time was associated with increased odds of developing MetS (OR = 1.40; 95%CI 1.01-1.94), and of a triglyceride level ≥ 150 mg/dL (OR = 1.48; 95%CI 1.08-2.03).
conclusionsAmong postmenopausal women in the WHI, sleep duration and insomnia were associated with current and future risk of MetS and some of its components.
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