Evidence map›Paper›PMID 36104685›Full record

ArticleJournal of nanobiotechnology2022

Multifunctional mesoporous silica-cerium oxide nanozymes facilitate miR129 delivery for high-quality healing of radiation-induced skin injury.

Daijun Zhou, Min Du, Han Luo, Fengwei Ran, Xiang Zhao, Yan Dong, Tao Zhang, Jie Hao, Dong Li, Jianjun Li

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
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  5. The Role and Mechanism of Nanozymes in Burn Wound Healing.International journal of nanomedicine · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Safety Landscape of Therapeutic Nanozymes and Future Research Directions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  14. Review
  15. Article
  16. Review
  17. Review
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Daijun ZhouDepartment of Oncology, General Hospital of Western Theater Command of PLA, Chengdu, 610083, China.
Min Du *Department of Oncology, General Hospital of Western Theater Command of PLA, Chengdu, 610083, China.
Han Luo *Department of Pulmonary and Critical Care Medicine, General Hospital of Western Theater Command of PLA, Chengdu, 610083, China.
Fengwei RanDepartment of Oncology, Southwest Cancer Center, Southwest Hospital, Army Medical University, 30 Gaotanyan Main St., Chongqing, 400038, China.
Xiang ZhaoDepartment of Oncology, Southwest Cancer Center, Southwest Hospital, Army Medical University, 30 Gaotanyan Main St., Chongqing, 400038, China.
Yan DongDepartment of Oncology, Southwest Cancer Center, Southwest Hospital, Army Medical University, 30 Gaotanyan Main St., Chongqing, 400038, China.
Tao ZhangDepartment of Oncology, General Hospital of Western Theater Command of PLA, Chengdu, 610083, China.
Jie HaoDepartment of Oncology, Southwest Cancer Center, Southwest Hospital, Army Medical University, 30 Gaotanyan Main St., Chongqing, 400038, China. haojie90@vip.qq.com.
Dong LiDepartment of Oncology, General Hospital of Western Theater Command of PLA, Chengdu, 610083, China. dongli81cd@qq.com.
Jianjun LiDepartment of Oncology, Southwest Cancer Center, Southwest Hospital, Army Medical University, 30 Gaotanyan Main St., Chongqing, 400038, China. sw-li@foxmail.com.
Army Medical University · CNChengdu Military General Hospital · CNSouthwest Hospital · CN

Funding

The General Program of Chongqing Natural Science Foundation cstc2021jcyj-msxmX0687the Medical and Industrial Combination Cultivation Program of Southwest Jiaotong University 2682021ZTPY019the Military Program of Army Medical University CX2019JS104the Program of General Hospital of Western Theater Command of PLA 2021-XZYG-B35
6 · The paper itself

Abstract

Radiation-induced skin injury (RISI) is an important challenge for clinical treatments. The main causes of RISI include hypoxia in the wound microenvironment, reactive oxygen species (ROS) activation, and downregulation of DNA repair proteins. Here, a multiple radioresistance strategy was designed for microRNA therapy and attenuating hypoxia. A novel mesoporous silica (MS) firmly anchored and dispersed cerium (IV) oxide (CeO

Indexed as

CeriumSilicon DioxideAnimalsHypoxiaMiceWound Healingceric oxideCeriumSilicon DioxideCeO2Mesoporous silicamiRNA-129Radiation-induced skin injury

Identifiers

PMID36104685
PMCPMC9476328
OpenAlexW4295900645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.