Evidence map›Paper›PMID 36104564›Full record

ArticleNature2022

Independent origins of fetal liver haematopoietic stem and progenitor cells.

Tomomasa Yokomizo, Takako Ideue, Saori Morino-Koga, Cheng Yong Tham, Tomohiko Sato, Naoki Takeda, Yoshiaki Kubota, Mineo Kurokawa, Norio Komatsu, Minetaro Ogawa and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
18.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 155 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. AbioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. DCAF13 Safeguards Hematopoietic Stem Cells via RRS1-Regulated Ribosome Biogenesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Mapping the Tissue-of-Origins of Mesenchymal Stromal Cells in Injury Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  15. Review
  16. Macrophages in Hematopoiesis and Related Blood Diseases.Genomics, proteomics & bioinformatics · 2025
    Review
  17. Article
  18. Review
  19. Article
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Tomomasa YokomizoInternational Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan. tomoyokomizo@gmail.com.ORCID http://orcid.org/0000-0001-6157-2852
Takako IdeueInternational Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan.
Saori Morino-KogaDepartment of Cell Differentiation, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan.
Cheng Yong ThamCancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.ORCID http://orcid.org/0000-0002-7594-3025
Tomohiko SatoDepartment of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-8244-075X
Naoki TakedaInstitute of Resource Development and Analysis, Kumamoto University, Kumamoto, Japan.
Yoshiaki KubotaDepartment of Anatomy, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0001-6672-4122
Mineo KurokawaDepartment of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Norio KomatsuDepartment of Hematology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Minetaro OgawaDepartment of Cell Differentiation, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan.ORCID http://orcid.org/0000-0002-4104-8911
Kimi ArakiInstitute of Resource Development and Analysis, Kumamoto University, Kumamoto, Japan.ORCID http://orcid.org/0000-0002-1396-1527
Motomi OsatoInternational Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan.ORCID http://orcid.org/0000-0003-3982-9054
Toshio SudaInternational Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan. csits@nus.edu.sg.ORCID http://orcid.org/0000-0001-7540-1771
Kumamoto University · JPNational University of Singapore · SGThe University of Tokyo · JPJuntendo University · JPKeio University · JPTokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Self-renewal and differentiation are tightly controlled to maintain haematopoietic stem cell (HSC) homeostasis in the adult bone marrow

Indexed as

Cell LineageFetusHematopoietic Stem CellsLiverAnimalsBasic-Leucine Zipper Transcription FactorsBone MarrowCell DifferentiationCell Self RenewalCell TrackingFemaleMDS1 and EVI1 Complex Locus ProteinMicePregnancyTranscription FactorsBasic-Leucine Zipper Transcription FactorsHlf protein, mouseMDS1 and EVI1 Complex Locus ProteinMecom protein, mouseTranscription Factors

Identifiers

PMID36104564
OpenAlexW4295763075

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.