Evidence map›Paper›PMID 36104498›Full record

ArticleArchives of toxicology2022

Ecstasy metabolites and monoamine neurotransmitters upshift the Na

Daniel José Barbosa, João Paulo Capela, Luísa Maria Ferreira, Paula Sério Branco, Eduarda Fernandes, Maria de Lourdes Bastos, Félix Carvalho

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. NaInternational journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Daniel José BarbosaTOXRUN - Toxicology Research Unit, University Institute of Health Sciences (IUCS), CESPU, CRL, Gandra, Portugal. daniel.barbosa@ibmc.up.pt.ORCID 0000-0002-1726-6011
João Paulo CapelaUCIBIO - Applied Molecular Biosciences Unit, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.ORCID 0000-0003-2607-1264
Luísa Maria FerreiraLAQV - REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, Universidade Nova de Lisboa, Caparica, Portugal.ORCID 0000-0001-8474-3925
Paula Sério BrancoLAQV - REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, Universidade Nova de Lisboa, Caparica, Portugal.ORCID 0000-0002-7312-8596
Eduarda FernandesLAQV - REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.ORCID 0000-0001-6424-0976
Maria de Lourdes BastosUCIBIO - Applied Molecular Biosciences Unit, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.ORCID 0000-0001-9895-503X
Félix CarvalhoUCIBIO - Applied Molecular Biosciences Unit, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal. felixdc@ff.up.pt.ORCID 0000-0003-3858-3494
Universidade do Porto · PTRede de Química e Tecnologia · PTFernando Pessoa University · PT

Funding

Fundação para a Ciência e a Tecnologia Project PTDC/SAU-FCF/102958/2008Fundação para a Ciência e a Tecnologia SFRH/BD/64939/2009
6 · The paper itself

Abstract

3,4-Methylenedioximethamphetamine (MDMA; "ecstasy") is a psychotropic drug with well-known neurotoxic effects mediated by hitherto not fully understood mechanisms. The Na

Indexed as

N-Methyl-3,4-methylenedioxyamphetamine3,4-Dihydroxyphenylacetic AcidAcetylcysteineAdenosineAdenosine TriphosphatasesAnimalsAntioxidantsBrainDeoxyepinephrineDopamineLevodopaMethylphenazonium MethosulfateMiceNeurotransmitter AgentsProtein KinasesSerotonin3,4-Dihydroxyphenylacetic AcidAcetylcysteineAdenosineAdenosine Triphosphatasesalpha-methyldopamineAntioxidantsDeoxyepinephrineDopamineLevodopaMethylphenazonium MethosulfateNeurotransmitter AgentsN-Methyl-3,4-methylenedioxyamphetamineProtein KinasesSerotoninSuperoxides3,4-Methylenedioxymethamphetamine (MDMA; “ecstasy”)MDMA brain effectsMDMA metabolitesMonoamine neurotransmittersNa+/K+ ATPaseSynaptosomes

Identifiers

PMID36104498
OpenAlexW4295786341

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.