ArticleScientific reports2022
Severity of COVID-19 cases in the months of predominance of the Alpha and Delta variants.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- Estimating the effect of self-protection on transmission dynamics of SARS-CoV-2 in Germany in 2021: a modelling study.BMC public health · 2026Article
- Disentangling the force of infection of SARS-CoV-2 in Dutch long-term care facilities.BMC public health · 2025Article
- Cognitive impairment 2 years after mild to severe SARS-CoV-2 infection in a population-based study with matched-comparison groups.Scientific reports · 2025Article
- Analysis of six consecutive waves of ICU-admitted COVID-19 patients: key findings and insights from a Portuguese population.GeroScience · 2025Article
- Changes in US drinking and alcohol use disorders associated with social, health, and economic impacts of COVID-19.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024Article
- Early pulmonary fibrosis-like changes between delta and pre-delta periods in patients with severe COVID-19 pneumonia on mechanical ventilation.Scientific reports · 2024Article
- The Role of Social Determinants of Health in Self-Reported Psychological Distress among United States Adults Post-COVID-19 Pandemic.International journal of environmental research and public health · 2024Article
- The impact of preoperative coronavirus disease 19 infection on early postoperative mortality during the vaccination era: a nationwide retrospective cohort study.Korean journal of anesthesiology · 2024Article
- COVID-19 in the Netherlands: lessons from a nationwide query of dutch autopsy, histology, and cytology pathological reports.Virchows Archiv : an international journal of pathology · 2024Review
- Clinical Epidemiology and Risk Factors for Critical Outcomes Among Vaccinated and Unvaccinated Adults Hospitalized With COVID-19-VISION Network, 10 States, June 2021-March 2023.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Mechanical ventilation as a major driver of COVID-19 hospitalization costs: a costing study in a German setting.Health economics review · 2024Article
- On the merits and potential of advanced neuroimaging techniques in COVID-19: A scoping review.NeuroImage. Clinical · 2024Article
- Impact of COVID infection on lung function test and quality of life.Scientific reports · 2023Article
- COVID-19 activity risk calculator as a gamified public health intervention tool.Scientific reports · 2023Article
- Epidemiological drivers of transmissibility and severity of SARS-CoV-2 in England.Nature communications · 2023Article
- COVID-19 Vaccination and Clinical Outcomes at a Secondary Referral Hospital During the Delta Variant-dominant Period in West Sumatra, Indonesia.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023Article
- SARS-CoV-2 Variants by Whole-Genome Sequencing in a University Hospital in Bangkok: First to Third COVID-19 Waves.Pathogens (Basel, Switzerland) · 2023Article
- Successive Waves of the COVID-19 Pandemic Had an Increasing Impact on Chronic Cardiovascular Patients in a Western Region of Romania.Healthcare (Basel, Switzerland) · 2023Article
- Social participation during the COVID-19 pandemic in persons with a high risk for a severe course of COVID-19 - results of a longitudinal, multi-center observational study in Germany.Health psychology and behavioral medicine · 2023Article
- Time series forecasting of COVID-19 infections and deaths in Alpha and Delta variants using LSTM networks.PloS one · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
New SARS-CoV-2 may pose problems in controlling the COVID-19 pandemic for public health. We aimed to assess and compare the symptoms and severity of cases due to the Alpha and Delta variant dominance periods, taking into account the effect of COVID-19 vaccination. A prospective epidemiological study of SARS-CoV-2 in Lleida was made to determine differences between Alpha and Delta variants periods. We assessed symptoms, specific comorbidities, sociodemographic information and vaccination status. Bivariate and logistic regression analyses were used to estimate the adjusted odds ratio (aOR) and 95% confidence intervals (CI) to investigate the relationship between symptoms and severity and the variants. Alpha variant period compared to the Delta showed an increased risk of ICU admission (aOR 2.0; 95% CI 1.2-2.3) and death (aOR 2.6; 95% CI 1.8-3.9) and cases were associated with people aged > 85 years (aOR 2.1; 95% CI 1.7-2.6) and partially vaccinated (aOR 5.6; 95% CI 3.2-9.9) and unvaccinated people (aOR 27.8; 95% CI 19.7-40.5). Fever, cough and vomiting were significantly associated with the Alpha variant compared to the Delta (aOR 1.6 (95% CI 1.5-1.7), 2.0 (95% CI 1.9-2.2) and 2.5 (95% CI 2.2-2.9, respectively). Our results show that the severity and profile of clinical symptoms varied according to the variant. The risk of ICU admission and death was higher in the Alpha period compared to the Delta as it affected the elderly and cases were less vaccinated.
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