Evidence map›Paper›PMID 36104353›Full record

ArticleNature communications2022

Mettl3-dependent m

Alexandra E Perlegos, Emily J Shields, Hui Shen, Kathy Fange Liu, Nancy M Bonini

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Heat Stress Promotes Fibroblast-Derived WNT5A Secretion Through mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. mInsects · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. mbioRxiv : the preprint server for biology · 2026
    Article
  10. High-stoichiometry mRNA (New York, N.Y.) · 2026
    Article
  11. Review
  12. Article
  13. Cocaine remodels mFrontiers in cellular neuroscience · 2026
    Article
  14. Article
  15. mActa pharmaceutica Sinica. B · 2025
    Review
  16. Epitranscriptomic reprogramming in response to low COThe Plant journal : for cell and molecular biology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Alexandra E PerlegosNeuroscience Graduate Group, University of Pennsylvania, Philadelphia, PA, 19104, USA.ORCID 0000-0002-4243-7644
Emily J ShieldsDepartment of Biology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Hui ShenDepartment of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Kathy Fange LiuDepartment of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.ORCID 0000-0001-5943-3888
Nancy M BoniniNeuroscience Graduate Group, University of Pennsylvania, Philadelphia, PA, 19104, USA. nbonini@sas.upenn.edu.ORCID 0000-0003-0226-5291
University of Pennsylvania · USUniversity Medical Center Freiburg · DE

Funding

TRAINING PROGRAM IN CELL AND MOLECULAR BIOLOGYT32GM007229 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BARTOLOMEI, MARISA S. · 1985 to 2023
$14.0M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
DROSOPHILA GENOMICS RESOURCE CENTERP40OD010949 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Andrew Zelhof · 2012 to 2026
$9.4M
Molecular Genetic Insight into Neurodegenerative Disease from DrosophilaR35NS097275 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI BONINI, NANCY M · 2017 to 2024
$6.0M
Coregulation of mRNA, tRNA, and rRNA species through RNA modificationsR35GM133721 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI LIU, FANGE · 2019 to 2023
$2.5M
Catalytic roles of RNA methyltransferase DIMT1R01HL160726 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI COOPERMAN, BARRY S., LIU, FANGE · 2022 to 2025
$2.4M
The in vivo role of m6A RNA modification in Cellular Stress, Aging, and Neurological ­DiseaseF31AG063470 · NIA · UNIVERSITY OF PENNSYLVANIA · PI PERLEGOS, ALEXANDRA EMILY · 2019 to 2021
$124k
NHLBI NIH HHS R01 HL160726NIA NIH HHS F31 AG063470NIGMS NIH HHS R01 GM084947NIGMS NIH HHS R35 GM133721NIGMS NIH HHS T32 GM007229NIH HHS P40 OD010949NIH HHS P40 OD018537NINDS NIH HHS R35 NS097275
6 · The paper itself

Abstract

N

Indexed as

AdenosineDrosophilaAnimalsBrainMethylationRNA, MessengerAdenosineRNA, Messenger

Identifiers

PMID36104353
PMCPMC9474545
OpenAlexW4295679071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.