Evidence map›Paper›PMID 36104195›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Lacosamide Intoxication-induced Wide QRS Tachycardia Successfully Treated with Veno-arterial Extracorporeal Membrane Oxygenation.

Chihiro Takai, Kayo Misumi, Daiki Kaito, Hiroaki Nishida, Masami Yoshii, So Yamada, Takaomi Kobayashi, Toshitaka Koinuma, Takashi Kadoya, Takuya Kimura and 2 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Case Report: Lacosamide unmaskingFrontiers in cardiovascular medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Chihiro TakaiDepartment of Emergency and Critical Care, Saiseikai Utsunomiya Hospital, Japan.
Kayo MisumiDepartment of Emergency and Critical Care, Saiseikai Utsunomiya Hospital, Japan.
Daiki KaitoDepartment of Emergency and Critical Care, Saiseikai Utsunomiya Hospital, Japan.
Hiroaki NishidaDepartment of Cardiology, Saiseikai Utsunomiya Hospital, Japan.
Masami YoshiiDepartment of Neurology, Saiseikai Utsunomiya Hospital, Japan.
So YamadaDepartment of Emergency and Critical Care, Saiseikai Utsunomiya Hospital, Japan.
Takaomi KobayashiDepartment of Emergency and Critical Care, Saiseikai Utsunomiya Hospital, Japan.
Toshitaka KoinumaDepartment of Emergency and Critical Care, Saiseikai Utsunomiya Hospital, Japan.
Takashi KadoyaDepartment of Emergency and Critical Care, Saiseikai Utsunomiya Hospital, Japan.
Takuya KimuraDepartment of Emergency and Critical Care, Saiseikai Utsunomiya Hospital, Japan.
Yoshihiro HagiwaraDepartment of Emergency and Critical Care, Saiseikai Utsunomiya Hospital, Japan.
Takayuki OguraDepartment of Emergency and Critical Care, Saiseikai Utsunomiya Hospital, Japan.
Saiseikai Utsunomiya hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lacosamide is an antiepileptic drug that acts on voltage-gated sodium channels and was approved as an antiepileptic by the Food and Drug Administration in 2008. Although the efficacy and safety of lacosamide have been established in many previous trials, some case reports have shown that it may lead to cardiovascular side effects, especially in patients with electrical conduction system disorders. We herein report a case of life-threatening cardiac arrhythmia caused by lacosamide intoxication that was successfully treated with veno-arterial extracorporeal membrane oxygenation.

Indexed as

Extracorporeal Membrane OxygenationAnticonvulsantsHumansLacosamideTachycardiaAnticonvulsantsLacosamideantiepilepticECMOelectrical stormlacosamidewide QRS tachycardia

Identifiers

PMID36104195
PMCPMC10183285
OpenAlexW4295903971

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.