Evidence map›Paper›PMID 36104054›Full record

ArticleSaudi medical journal2022

Epicardial adipose tissue thickness and growth differentiation factor 15 in axial spondyloarthritis: A cross-sectional study.

Mehmet Okçu, Fatmanur A Koçak, Senem Şaş, Kenan Güçlü

Open access · diamondAbstract read
In one paragraph

Article in Saudi medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mehmet OkçuFrom the Department of Physical Medicine and Rehabilitation (Okçu), Marmara University Faculty of Medicine, Istanbul; from the Department of Physical Medicine and Rehabilitation (Koçak), Kırsehir Ahi Evran University Faculty of Medicine; from the Department of Physical Medicine and Rehabilitation (Şaş), Division of Rheumatology, Kayseri, Erciyes University Faculty of Medicine; and from the Department of Biochemistry (Güçlü), Kırsehir Ahi Evran University Faculty of Medicine, Kırsehir, Turkey.
Fatmanur A KoçakFrom the Department of Physical Medicine and Rehabilitation (Okçu), Marmara University Faculty of Medicine, Istanbul; from the Department of Physical Medicine and Rehabilitation (Koçak), Kırsehir Ahi Evran University Faculty of Medicine; from the Department of Physical Medicine and Rehabilitation (Şaş), Division of Rheumatology, Kayseri, Erciyes University Faculty of Medicine; and from the Department of Biochemistry (Güçlü), Kırsehir Ahi Evran University Faculty of Medicine, Kırsehir, Turkey.
Senem ŞaşFrom the Department of Physical Medicine and Rehabilitation (Okçu), Marmara University Faculty of Medicine, Istanbul; from the Department of Physical Medicine and Rehabilitation (Koçak), Kırsehir Ahi Evran University Faculty of Medicine; from the Department of Physical Medicine and Rehabilitation (Şaş), Division of Rheumatology, Kayseri, Erciyes University Faculty of Medicine; and from the Department of Biochemistry (Güçlü), Kırsehir Ahi Evran University Faculty of Medicine, Kırsehir, Turkey.
Kenan GüçlüFrom the Department of Physical Medicine and Rehabilitation (Okçu), Marmara University Faculty of Medicine, Istanbul; from the Department of Physical Medicine and Rehabilitation (Koçak), Kırsehir Ahi Evran University Faculty of Medicine; from the Department of Physical Medicine and Rehabilitation (Şaş), Division of Rheumatology, Kayseri, Erciyes University Faculty of Medicine; and from the Department of Biochemistry (Güçlü), Kırsehir Ahi Evran University Faculty of Medicine, Kırsehir, Turkey.
Ahi Evran University · TRErciyes University · TRMarmara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate growth differentiation factor-15 (GDF-15) levels and the thickness of epicardial adipose tissue (EAT) in patients with axial spondyloarthritis (axSpA) and to evaluate their relationship with functional status, disease activity, disease duration, and the type of medical treatment received by the patients.

methodsThis cross-sectional study was carried out at Kırşehir Ahievran University School of Medicine between February and June 2020. Twenty-nine healthy controls and 44 patients with axSpA were included in the study. Gender, age, erythrocyte sedimentation rate, GDF-15, body mass index, complete blood count, ejection fraction, the EAT thickness, and C-reactive protein of all participants were recorded. Ankylosing Spondylitis Quality of Life Index, Bath Ankylosing Spondylitis Functional Index, the disease duration, Bath Ankylosing Spondylitis Metrology Index, and Bath Ankylosing Spondylitis Disease Activity Index scores of patients with axSpA were noted.

resultsEpicardial adipose tissue thickness values (0.35±0.09 cm) in the AxSpA group were higher compared to the control group (0.26±0.06 cm) (

conclusionIn this study, EAT thickness values were found to be significantly higher in the axSpA group. In addition, GDF-15 was positively correlated with age, Bath Ankylosing Spondylitis Functional Index score, and disease duration.

Indexed as

Axial SpondyloarthritisSpondylitis, AnkylosingAdipose TissueCross-Sectional StudiesGrowth Differentiation Factor 15HumansQuality of LifeGDF15 protein, humanGrowth Differentiation Factor 15ankylosing spondylitisaxial spondylarthritisepicardial adipose tissuegrowth differentiation factor 15

Identifiers

PMID36104054
PMCPMC9987668
OpenAlexW4295561343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.