Evidence map›Paper›PMID 36103825›Full record

ArticleCell reports2022

Activation of VIP interneurons in the prefrontal cortex ameliorates neuropathic pain aversiveness.

Miao Li, Hang Zhou, Sasa Teng, Guang Yang

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 26 citations in OpenAlex.

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  7. A neuron type-specific microexon inbioRxiv : the preprint server for biology · 2025
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  11. Role and mechanisms of interneurons in chronic pain and pain-induced cognitive impairment.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Miao LiDepartment of Anesthesiology, Columbia University Medical Center, New York, NY 10032, USA.
Hang ZhouDepartment of Anesthesiology, Columbia University Medical Center, New York, NY 10032, USA.
Sasa TengInstitute for Genomic Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Guang YangDepartment of Anesthesiology, Columbia University Medical Center, New York, NY 10032, USA. Electronic address: gy2268@cumc.columbia.edu.
Columbia University Irving Medical Center · USColumbia University · US

Funding

The roles of anesthetics and neuroimmune interactions in postoperative cognitive dysfunctionR35GM131765 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Guang Yang · 2019 to 2026
$3.4M
The role of neuroimmune interactions in the pathogenesis of chronic painR01AA027108 · NIAAA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHAO, MOSES VICTOR, YANG, GUANG · 2018 to 2022
$2.9M
NIAAA NIH HHS R01 AA027108NIGMS NIH HHS R35 GM131765
6 · The paper itself

Abstract

While dysfunction of the medial prefrontal cortex (mPFC) has been implicated in chronic pain, the underlying neural circuits and the contribution of specific cellular populations remain unclear. Using in vivo Ca

Indexed as

NeuralgiaVasoactive Intestinal PeptideAnimalsFemaleGyrus CinguliInterneuronsMaleMicePrefrontal CortexVasoactive Intestinal Peptideanterior cingulate cortexcalcium imagingCP: Neurosciencemedial prefrontal cortexneuropathic painprelimbic cortexpyramidal neuronsvasoactive intestinal polypeptide-expressing interneurons

Identifiers

PMID36103825
PMCPMC9520588
OpenAlexW4295901333

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.