Evidence map›Paper›PMID 36103583›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

The Lung Allograft Microbiome Associates with Pepsin, Inflammation, and Primary Graft Dysfunction.

John E McGinniss, Samantha A Whiteside, Rebecca A Deek, Aurea Simon-Soro, Jevon Graham-Wooten, Michelle Oyster, Melanie D Brown, Edward Cantu, Joshua M Diamond, Hongzhe Li and 3 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Lung allograft dysbiosis associates with immune response and primary graft dysfunction.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2025
    Article
  8. Article
  9. Beyond the organ: lung microbiome shapes transplant indications and outcomes.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024
    Review
  10. Reply to WardAmerican journal of respiratory and critical care medicine · 2024
    Article
  11. Lung Transplant Outcomes Keep BUGging us: Acute Cellular Rejection and the Lung Microbiome.American journal of respiratory and critical care medicine · 2024
    Article
  12. Longitudinal Lower Airway Microbial Signatures of Acute Cellular Rejection in Lung Transplantation.American journal of respiratory and critical care medicine · 2024
    Article
  13. Article
  14. Article
  15. The impact of the EVLP on the lung microbiome and its inflammatory reaction.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  16. Article
  17. Lung Allograft Dysfunction: Does Aspiration Hold the Key?American journal of respiratory and critical care medicine · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

John E McGinnissDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.ORCID 0000-0002-6451-5121
Samantha A WhitesideDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.ORCID 0000-0002-0088-3101
Rebecca A DeekDepartment of Epidemiology, Biostatistics, and Informatics.ORCID 0000-0002-8783-4694
Aurea Simon-SoroDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.ORCID 0000-0003-3656-6834
Jevon Graham-WootenDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.
Michelle OysterDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.
Melanie D BrownDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.
Edward CantuDepartment of Surgery, and.
Joshua M DiamondDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.
Hongzhe LiDepartment of Epidemiology, Biostatistics, and Informatics.ORCID 0000-0003-3662-3907
Jason D ChristieDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.ORCID 0000-0003-0519-218X
Frederic D BushmanDepartment of Microbiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0003-4740-4056
Ronald G CollmanDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.ORCID 0000-0002-0508-3701
Pulmonary and Allergy Associates · USInstitute for Medical Informatics and Biostatistics · CHUniversity of Pennsylvania · US

Funding

Institutional Clinical and Translational Science AwardKL2TR001879 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI MEAGHER, EMMA ANNE · 2016 to 2025
$13.7M
Long Term Follow up of the Lung Transplant Outcomes Group CohortU01HL145435 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D, PALMER, SCOTT M · 2019 to 2025
$10.2M
Clinical Risk Factors for Primary Graft DysfunctionR01HL087115 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D · 2007 to 2017
$7.1M
The Lung DNA Virome in Health and DiseaseR33HL137063 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI BUSHMAN, FREDERIC D, COLLMAN, RONALD G · 2019 to 2021
$2.3M
Mentored Patient Oriented Research in Lung TransplantationK24HL115354 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D · 2012 to 2021
$1.2M
Host-microbiome interactions after lung transplantation and chronic lung allograft dysfunctionK23HL158068 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MCGINNISS, JOHN EVAN · 2021 to 2022
$387k
Advanced diagnostics for donor lung assessment and ex vivo lung perfusion candidate selectionR03HL135227 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CANTU, EDWARD · 2016 to 2017
$161k
NCATS NIH HHS KL2 TR001879NCATS NIH HHS KL2-TR001879NHLBI NIH HHS K23 HL158068NHLBI NIH HHS K23-HL158068NHLBI NIH HHS K24 HL115354NHLBI NIH HHS L30 HL149040NHLBI NIH HHS R01 HL087115NHLBI NIH HHS R03 HL135227NHLBI NIH HHS R33 HL137063NHLBI NIH HHS U01 HL145435NIH HHS K24HL115354NIH HHS R01-HL087115NIH HHS R01-HL113256NIH HHS R03-HL135227NIH HHS R33-HL137063NIH HHS U01-HL145435
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lung TransplantationMicrobiotaPrimary Graft DysfunctionAllograftsCytokinesHumansInflammationLungPepsin AProspective StudiesCytokinesPepsin Ahost–microbe interactionslung transplantationmicrobiomeprimary graft dysfunction

Identifiers

PMID36103583
PMCPMC9757091
OpenAlexW4295786330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.