Evidence map›Paper›PMID 36103254›Full record

ArticleACS macro letters2022

Functionalized Hyaluronic Acid for "

Susi Burgalassi, Marco Fragai, Oscar Francesconi, Linda Cerofolini, Daniela Monti, Gemma Leone, Stefania Lamponi, Giuseppe Greco, Agnese Magnani, Cristina Nativi

Open access · hybridAbstract read
In one paragraph

Article in ACS macro letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. CD8American journal of translational research · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Susi BurgalassiDepartment of Pharmacy, University of Pisa, via Bonanno 6, 56126 Pisa, Italy.
Marco FragaiDepartment of Chemistry (DICUS), University of Florence, Sesto Fiorentino 50019, Italy.ORCID 0000-0002-8440-1690
Oscar FrancesconiDepartment of Chemistry (DICUS), University of Florence, Sesto Fiorentino 50019, Italy.ORCID 0000-0002-6155-4926
Linda CerofoliniCIRMMP, University of Florence, via Sacconi, 6 Sesto Fiorentino 50019, Italy.
Daniela MontiDepartment of Pharmacy, University of Pisa, via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0001-7622-4367
Gemma LeoneDepartment of Biotechnology, Chemistry and Pharmacy, via A. Moro, 2 53100 Siena, Italy.
Stefania LamponiDepartment of Biotechnology, Chemistry and Pharmacy, via A. Moro, 2 53100 Siena, Italy.
Giuseppe GrecoRugani Hospital, SR222 Chiantigiana, 53035 Colombaio (Siena), Italy.
Agnese MagnaniDepartment of Biotechnology, Chemistry and Pharmacy, via A. Moro, 2 53100 Siena, Italy.ORCID 0000-0002-6960-9418
Cristina NativiDepartment of Chemistry (DICUS), University of Florence, Sesto Fiorentino 50019, Italy.ORCID 0000-0002-6312-3230
Interuniversity Consortium for Magnetic Resonance · ITNational Interuniversity Consortium of Materials Science and Technology · ITUniversity of Pisa · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyaluronic acid (HA) is a naturally occurring polysaccharide with many molecular functions, including maintaining the structure and physiology of the tissues, tissue remodeling, and inflammation. HA is found naturally in physiological tear fluid, possesses excellent mucus-layer-adhesive properties, and is successfully employed in the treatment of dry eye syndrome (DES). However, HA has as major drawback: its rapid

Indexed as

Dry Eye SyndromesHyaluronic AcidHumansHyaluronoglucosaminidaseMatrix MetalloproteinasesPolysaccharidesHyaluronic AcidHyaluronoglucosaminidaseMatrix MetalloproteinasesPolysaccharides

Identifiers

PMID36103254
PMCPMC9583614
OpenAlexW4295756238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.