Evidence map›Paper›PMID 36103225›Full record

ArticleJMIR formative research2022

Measuring Daily Activity Rhythms in Young Adults at Risk of Affective Instability Using Passively Collected Smartphone Data: Observational Study.

Benny Ren, Cedric Huchuan Xia, Philip Gehrman, Ian Barnett, Theodore Satterthwaite

Open access · goldAbstract read
In one paragraph

Article in JMIR formative research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Benny RenDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0001-6075-657X
Cedric Huchuan XiaPenn Lifespan Informatics and Neuroimaging Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0002-9703-333X
Philip GehrmanDepartment of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0003-1054-7475
Ian BarnettDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0003-3256-5703
Theodore SatterthwaitePenn Lifespan Informatics and Neuroimaging Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0001-7072-9399
Lifespan · USUniversity of Pennsylvania · USPhiladelphia VA Medical Center · US

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
Longitudinal Mapping of Network Development Underlying Executive Dysfunction in AdolescenceR01MH113550 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Danielle Smith Bassett, Theodore Satterthwaite · 2018 to 2026
$6.9M
Longitudinal multi-modal neuroimaging of irritability in youthR01MH107703 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI SATTERTHWAITE, THEODORE · 2015 to 2018
$2.6M
Statistical methods in mHealth to signal interventional needs for mental health patientsR01MH116884 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI BARNETT, IAN JAMES · 2019 to 2022
$1.6M
NCATS NIH HHS UL1 TR001878NIMH NIH HHS R01 MH107703NIMH NIH HHS R01 MH113550NIMH NIH HHS R01 MH116884
6 · The paper itself

Abstract

backgroundIrregularities in circadian rhythms have been associated with adverse health outcomes. The regularity of rhythms can be quantified using passively collected smartphone data to provide clinically relevant biomarkers of routine.

objectiveThis study aims to develop a metric to quantify the regularity of activity rhythms and explore the relationship between routine and mood, as well as demographic covariates, in an outpatient psychiatric cohort.

methodsPassively sensed smartphone data from a cohort of 38 young adults from the Penn or Children's Hospital of Philadelphia Lifespan Brain Institute and Outpatient Psychiatry Clinic at the University of Pennsylvania were fitted with 2-state continuous-time hidden Markov models representing active and resting states. The regularity of routine was modeled as the hour-of-the-day random effects on the probability of state transition (ie, the association between the hour-of-the-day and state membership). A regularity score, Activity Rhythm Metric, was calculated from the continuous-time hidden Markov models and regressed on clinical and demographic covariates.

resultsRegular activity rhythms were associated with longer sleep durations (P=.009), older age (P=.001), and mood (P=.049).

conclusionsPassively sensed Activity Rhythm Metrics are an alternative to existing metrics but do not require burdensome survey-based assessments. Low-burden, passively sensed metrics based on smartphone data are promising and scalable alternatives to traditional measurements.

Indexed as

circadian rhythmhidden Markov modelmental healthmHealthmobile healthmobile phone

Identifiers

PMID36103225
PMCPMC9520392
OpenAlexW4285822416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.