Evidence map›Paper›PMID 36103048›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2022

Interaction between gut microbiota and tumour chemotherapy.

Le Liu, Yuping Bai, Lin Xiang, Wenbo Qi, Lei Gao, Xiaomei Li, Haiyuan Li, Bofang Wang, Hao Chen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Le LiuThe Second Clinical Medical College of Lanzhou University, Lanzhou, 730000, China.
Yuping BaiThe Second Clinical Medical College of Lanzhou University, Lanzhou, 730000, China.
Lin XiangThe Second Clinical Medical College of Lanzhou University, Lanzhou, 730000, China.
Wenbo QiThe Second Clinical Medical College of Lanzhou University, Lanzhou, 730000, China.
Lei GaoThe Second Clinical Medical College of Lanzhou University, Lanzhou, 730000, China.
Xiaomei LiThe Second Clinical Medical College of Lanzhou University, Lanzhou, 730000, China.
Haiyuan LiThe Second Clinical Medical College of Lanzhou University, Lanzhou, 730000, China.
Bofang WangThe Second Clinical Medical College of Lanzhou University, Lanzhou, 730000, China.
Hao ChenThe Second Clinical Medical College of Lanzhou University, Lanzhou, 730000, China. ery_chenh@lzu.edu.cn.ORCID http://orcid.org/0000-0003-0018-480X

Funding

Key Talents Project of Gansu Province 2019RCXM020Research Fund of Gansu Provincial People's Hospital 21GSSYB-3
6 · The paper itself

Abstract

Chemotherapeutic drugs play an important role in the treatment of cancer, but the individual differences of patients' sensitivity to chemotherapeutic drugs and the drug resistance of chemotherapeutic drugs have always been a thorny problem in clinical treatment. In recent years, with the progress in research on human microbiota, gut microbiome plays an increasingly important role in the diagnosis and treatment of diseases. Studies have shown that gut microbiota can regulate the tumour microenvironment and affect the efficacy and toxicity of chemotherapy through a variety of mechanisms. This paper focuses on the specific mechanism that gut microbiota uses to influence chemotherapy and the potential therapeutic effect of supplementing with probiotics, to provide an important basis for individualised treatment strategies to be used when treating malignant tumours.

Indexed as

Gastrointestinal MicrobiomeMicrobiotaNeoplasmsProbioticsHumansTumor MicroenvironmentAdverse reactionsChemotherapyCurative effectGut microbiota

Identifiers

PMID36103048

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.