Evidence map›Paper›PMID 36102656›Full record

ArticleInfection and immunity2022

FtlA and FtlB Are Candidates for Inclusion in a Next-Generation Multiantigen Subunit Vaccine for Lyme Disease.

Andrew C Camire, Nathaniel S O'Bier, Dhara T Patel, Nicholas A Cramer, Reinhard K Straubinger, Edward B Breitschwerdt, Rebecca A Funk, Richard T Marconi

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Infection and immunity · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Andrew C CamireDepartment of Microbiology and Immunology, Virginia Commonwealth University Medical Centergrid.417264.2, Richmond, Virginia, USA.
Nathaniel S O'BierDepartment of Microbiology and Immunology, Virginia Commonwealth University Medical Centergrid.417264.2, Richmond, Virginia, USA.
Dhara T PatelDepartment of Microbiology and Immunology, Virginia Commonwealth University Medical Centergrid.417264.2, Richmond, Virginia, USA.
Nicholas A CramerDepartment of Microbiology and Immunology, Virginia Commonwealth University Medical Centergrid.417264.2, Richmond, Virginia, USA.
Reinhard K StraubingerInstitute of Infectious Diseases and Zoonoses, Department of Veterinary Sciences, Faculty of Veterinary Medicine, Ludwig-Maximilians-University, Munich, Germany.
Edward B BreitschwerdtDepartment of Clinical Sciences, The Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
Rebecca A FunkDepartment of Large Animal Clinical Sciences, VA-MD College of Veterinary Medicine, Blacksburg, Virginia, USA.
Richard T MarconiDepartment of Microbiology and Immunology, Virginia Commonwealth University Medical Centergrid.417264.2, Richmond, Virginia, USA.ORCID 0000-0002-6035-7306
Virginia Commonwealth University Medical Center · USLudwig-Maximilians-Universität München · DENorth Carolina State University · USVirginia Commonwealth University · USVirginia–Maryland College of Veterinary Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lyme disease (LD) is a tick-transmitted bacterial infection caused by Borreliella burgdorferi and other closely related species collectively referred to as the LD spirochetes. The LD spirochetes encode an uncharacterized family of proteins originally designated

Indexed as

Borrelia burgdorferiIxodesLyme DiseaseAnimalsAntibodies, BacterialAntigens, BacterialBacterial Outer Membrane ProteinsDogsEpitopesHorsesImmune SeraLipoproteinsVaccines, CombinedVaccines, SubunitAntibodies, BacterialAntigens, BacterialBacterial Outer Membrane ProteinsEpitopesImmune SeraLipoproteinsVaccines, CombinedVaccines, SubunitBBG01BBK01BorreliaBorreliellacanine Lyme diseasechimeritopeFtlFtlAIxodesLyme disease vaccineLyme vaccinePF12protein family 12

Identifiers

PMID36102656
PMCPMC9584329
OpenAlexW4295678944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.