Evidence map›Paper›PMID 36102600›Full record

ArticleVeterinary surgery : VS2022

Wound swabs versus biopsies to detect methicillin resistant Staphylococcus aureus in experimental equine wounds.

Abbi K Brock, Ana M Chamoun-Emanuelli, Emily A Howard, Katie D Huntzinger, Sara D Lawhon, Laura K Bryan, Elizabeth M Cosgriff-Hernandez, Noah D Cohen, Canaan M Whitfield-Cargile

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary surgery : VS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Abbi K BrockDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, Texas, USA.
Ana M Chamoun-EmanuelliDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, Texas, USA.
Emily A HowardDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, Texas, USA.
Katie D HuntzingerDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, Texas, USA.
Sara D LawhonDepartment of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, Texas, USA.
Laura K BryanDepartment of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, Texas, USA.
Elizabeth M Cosgriff-HernandezDepartment of Biomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, Texas, USA.
Noah D CohenDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, Texas, USA.
Canaan M Whitfield-CargileDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, Texas, USA.
Texas A&M University · USThe University of Texas at Austin · US

Funding

Antimicrobial Hydrogel Foam Dressings for Infected Chronic WoundsR21AR076107 · NIAMS · UNIVERSITY OF TEXAS AT AUSTIN · PI COSGRIFF-HERNANDEZ, ELIZABETH MARIE · 2020 to 2021
$367k
Department of Large Animal Clinical Sciences, Texas A&M University RGS 20-08NIAMS NIH HHS R21 AR076107NIH HHS NIAMS R21AR076107
6 · The paper itself

Abstract

objectiveTo compare: (1) the load and diversity of cultivatable bacterial species isolated from tissue biopsies with cultures from surface swabs, and (2) the ability of each technique to detect methicillin-resistant Staphylococcus aureus (MRSA) in a model of MRSA-infected equine wounds. STUDY

designExperimental in vivo study. ANIMALS: Three light-breed adult horses.

methodsFour 2.5 × 2.5 cm full-thickness skin wounds were created on the dorsolateral aspect of each forelimb. Five days later, each wound was inoculated with a pure culture of MRSA (ATCC 43300). One hundred microlitres of 0, 5 × 10

resultsA similar bacterial profile was identified from the culture of each wound-sampling technique and there was moderate correlation (R = 0.49, P < .001) between the bacterial bioburdens. Agreement was fair (κ = 0.31; 95% CI, 0.129-0.505) between the sampling techniques in identification of MRSA. Methicillin-resistant Staphylococcus aureus was isolated more frequently (P = .016) from cultures of tissue biopsies (79%; 76/96) than from surface swabs (62%; 60/96).

conclusionBacterial load and diversity did not differ between sampling techniques but MRSA was detected more often from the cultures of tissue biopsies. CLINICAL SIGNIFICANCE: Tissue biopsy should be preferred to culture swab in wounds where MRSA is suspected.

Indexed as

Horse DiseasesMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsWound InfectionAnimalsBiopsyHorsesSpecimen Handling

Identifiers

PMID36102600
PMCPMC9588683
OpenAlexW4295752422

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.