Evidence map›Paper›PMID 36102571›Full record

ArticleACS applied materials & interfaces2022

Delivering Multifunctional Peptide-Conjugated Gene Carrier/miRNA-218 Complexes from Monodisperse Microspheres for Bone Regeneration.

Qian Li, Yuejia Deng, Xiaohua Liu

Open access · greenAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Carbon dots-based drug delivery for bone regeneration.Frontiers in bioengineering and biotechnology · 2025
    Review
  3. Multifunctional Nanofibrous Hollow Microspheres for Enhanced Periodontal Bone Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Qian LiDepartment of Biomedical Sciences, Texas A&M University School of Dentistry, Dallas, Texas 75246, United States.
Yuejia DengDepartment of Biomedical Sciences, Texas A&M University School of Dentistry, Dallas, Texas 75246, United States.
Xiaohua LiuDepartment of Biomedical Sciences, Texas A&M University School of Dentistry, Dallas, Texas 75246, United States.ORCID 0000-0003-0177-0886
Texas A&M University · US

Funding

Polarization of dental pulp stem cellsR21DE029860 · NIDCR · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI LIU, XIAOHUA · 2020 to 2021
$416k
NIDCR NIH HHS R21 DE029860
6 · The paper itself

Abstract

MicroRNAs (miRNAs) play a pivotal role in regulating gene expression and are considered new molecular targets in bone tissue engineering. However, effective delivery of miRNAs to the defect areas and transfection of the miRNAs into osteogenic progenitor cells has been an obstacle in the application. In this work, miRNA-218 (miR-218) was used as an osteogenic miRNA regulator, and a multifunctional peptide-conjugated gene carrier poly(lactide-

Indexed as

MicroRNAsBone RegenerationGelatinMethacrylatesMicrospheresOsteogenesisPeptidesPolyethylene GlycolsPolyethyleneiminePolyglactin 910Gelatingelatin methacryloylMethacrylatesMicroRNAsPeptidesPolyethylene GlycolsPolyethyleneiminePolyglactin 910bone regenerationmicrofluidicsmicrospheremiR-218photo-cross-linking

Identifiers

PMID36102571
PMCPMC10016386
OpenAlexW4295753594

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.