ArticleRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2022
Comparison of mortality and survival without major morbidities of very preterm infants with very low birth weight from Japan and Brazil.
Article in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Prevalence of survival without major morbidity and associated risk factors among very preterm infants: a systematic review and meta-analysis.Frontiers in pediatrics · 2025Pooled it
- Transcatheter-Based Palliation of Congenital Heart Disease in Very Low Birth Weight Infants.JACC. Case reports · 2026Article
- Morbidity and Mortality of Very-Low-Birth-Weight Preterm Neonates in a Tertiary Neonatal Intensive Care Unit in Northeastern Mexico: A Five-Year Retrospective Cohort Study.Pediatric reports · 2026Article
- Association between initial empirical antibiotic therapy and necrotizing enterocolitis in very preterm infants at different risk for early-onset sepsis: a multicenter cohort study.BMC pregnancy and childbirth · 2026Observational
- Survival without major morbidity in very preterm infants (<32 weeks' gestation): prevalence, temporal trends, and associated factors in a single-center retrospective cohort.Frontiers in pediatrics · 2026Article
- Impact of Pulmonary Hypertension and Patent Ductus Arteriosus in Preterm Infants with Presumed Pulmonary Hypoplasia.Biomedicines · 2025Article
- Epidemiology and management of infections in critically ill neonates: findings from a cohort study in a Brazilian neonatal intensive care unit.Journal of medical microbiology · 2025Article
- Survival and morbidity in very preterm infants in Shenzhen: a multi-center study.Frontiers in pediatrics · 2023Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study was carried out to understand the disparities in mortality and survival without major morbidities among very premature and very low birth weight infants between participating Neonatal Intensive Care Units (NICUs) from the Brazilian Network on Neonatal Research (RBPN) and the Neonatal Research Network of Japan (NRNJ).
methodsSecondary data analysis of surveys by the RBPN and NRNJ was performed. The surveys were conducted in 2014 and 2015 and included 187 NICUs. Primary outcome was mortality or survival without any major morbidity. Logistic regression analysis adjustment for confounding factors was used.
resultsThe study population consisted of 6,406 infants from the NRNJ and 2,319 from the RBPN. Controlling for various confounders, infants from RBPN had 9.06 times higher adjusted odds of mortality (95%CI 7.30-11.29), and lower odds of survival without major morbidities (AOR 0.36; 95%CI 0.32-0.41) compared with those from the NRNJ. Factors associated with higher odds of mortality among Brazilian NICUs included: Air Leak Syndrome (AOR 4.73; 95%CI 1.26-15.27), Necrotizing Enterocolitis (AOR 3.25; 95%CI 1.38-7.26), and Late Onset Sepsis (LOS) (AOR 4.86; 95%CI 2.25-10.97).
conclusionsVery premature and very low birth weight infants from Brazil had significantly higher odds for mortality and lower odds for survival without major morbidities in comparison to those from Japan. Additionally, we identified the factors that increased the odds of in-hospital neonatal death in Brazil, most of which was related to LOS.
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