Evidence map›Paper›PMID 36102318›Full record

ArticleOncology reports2022

Wnt2b and Wnt5a expression is highly associated with M2 TAMs in non‑small cell lung cancer.

Ryota Sumitomo, Cheng-Long Huang, Hidenori Ando, Tatsuhiro Ishida, Hiroyuki Cho, Hiroshi Date

Open access · bronzeAbstract read
In one paragraph

Article in Oncology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Bioinformatic Analysis of WNT Family Proteins.Bioinformatics and biology insights · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. The Roles of Secreted Wnt Ligands in Cancer.International journal of molecular sciences · 2023
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ryota SumitomoDepartment of Thoracic Surgery, Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka 530‑8480, Japan.
Cheng-Long HuangDepartment of Thoracic Surgery, Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka 530‑8480, Japan.
Hidenori AndoDepartment of Pharmacokinetics and Biopharmaceutics, Institute of Biomedical Science, Tokushima University, Tokushima 770‑8505, Japan.
Tatsuhiro IshidaDepartment of Pharmacokinetics and Biopharmaceutics, Institute of Biomedical Science, Tokushima University, Tokushima 770‑8505, Japan.
Hiroyuki ChoDepartment of Thoracic Surgery, Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka 530‑8480, Japan.
Hiroshi DateDepartment of Thoracic Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606‑8507, Japan.
Kitano Hospital · JPTokushima University · JPKyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor‑associated macrophages (TAMs), particularly M2 macrophages, promote tumor progression, while

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsGlycoproteinsHumansImmunohistochemistryKi-67 AntigenTumor-Associated MacrophagesWnt-5a ProteinWnt ProteinsGlycoproteinsKi-67 AntigenWNT2B protein, humanWnt-5a ProteinWNT5A protein, humanWnt ProteinsCD163Ki‑67lung cancermacrophageWnt2bWnt5a

Identifiers

PMID36102318
PMCPMC9500576
OpenAlexW4295756823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.