Evidence map›Paper›PMID 36102226›Full record

ArticleJournal of the American Heart Association2022

Enriching the American Heart Association COVID-19 Cardiovascular Disease Registry Through Linkage With External Data Sources: Rationale and Design.

Andrew S Oseran, Tianyu Sun, Rishi K Wadhera, Issa J Dahabreh, James A de Lemos, Sandeep R Das, Christine Rutan, Aarti H Asnani, Robert W Yeh, Dhruv S Kazi

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrew S OseranRichard A. and Susan F. Smith Center for Outcomes Research Beth Israel Deaconess Medical Center Boston MA.ORCID 0000-0002-5810-5927
Tianyu SunRichard A. and Susan F. Smith Center for Outcomes Research Beth Israel Deaconess Medical Center Boston MA.ORCID 0000-0002-3996-1381
Rishi K WadheraRichard A. and Susan F. Smith Center for Outcomes Research Beth Israel Deaconess Medical Center Boston MA.ORCID 0000-0003-1089-3896
Issa J DahabrehRichard A. and Susan F. Smith Center for Outcomes Research Beth Israel Deaconess Medical Center Boston MA.ORCID 0000-0002-2215-9931
James A de LemosDivision of Cardiology University of Texas Southwestern Medical Center Dallas TX.ORCID 0000-0003-2211-7261
Sandeep R DasDivision of Cardiology University of Texas Southwestern Medical Center Dallas TX.ORCID 0000-0002-8454-1925
Christine RutanQuality, Outcomes Research and Analytics American Heart Association Dallas TX.ORCID 0000-0002-5071-1607
Aarti H AsnaniDivision of Cardiology Beth Israel Deaconess Medical Center and Harvard Medical School Boston MA.ORCID 0000-0003-4967-9918
Robert W YehRichard A. and Susan F. Smith Center for Outcomes Research Beth Israel Deaconess Medical Center Boston MA.ORCID 0000-0002-0564-4468
Dhruv S KaziRichard A. and Susan F. Smith Center for Outcomes Research Beth Israel Deaconess Medical Center Boston MA.ORCID 0000-0002-9510-2979

Funding

A Multi-Dimensional Linked Registry to Identify Biological, Clinical, Health System, and Socioeconomic Risk Factors for COVID-19-Related Cardiovascular EventsR01HL157530 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI GERSZTEN, ROBERT E, KAZI, DHRUV SATISH · 2021 to 2024
$3.0M
NHLBI NIH HHS R01 HL157530
6 · The paper itself

Abstract

Background The AHA Registry (American Heart Association COVID-19 Cardiovascular Disease Registry) captures detailed information on hospitalized patients with COVID-19. The registry, however, does not capture information on social determinants of health or long-term outcomes. Here we describe the linkage of the AHA Registry with external data sources, including fee-for-service (FFS) Medicare claims, to fill these gaps and assess the representativeness of linked registry patients to the broader Medicare FFS population hospitalized with COVID-19. Methods and Results We linked AHA Registry records of adults ≥65 years from March 2020 to September 2021 with Medicare FFS claims using a deterministic linkage algorithm and with the American Hospital Association Annual Survey, Rural Urban Commuting Area codes, and the Social Vulnerability Index using hospital and geographic identifiers. We compared linked individuals with unlinked FFS beneficiaries hospitalized with COVID-19 to assess the representativeness of the AHA Registry. A total of 10 010 (47.0%) records in the AHA Registry were successfully linked to FFS Medicare claims. Linked and unlinked FFS beneficiaries were similar with respect to mean age (78.1 versus 77.9, absolute standardized difference [ASD] 0.03); female sex (48.3% versus 50.2%, ASD 0.04); Black race (15.1% versus 12.0%, ASD 0.09); dual-eligibility status (26.1% versus 23.2%, ASD 0.07); and comorbidity burden. Linked patients were more likely to live in the northeastern United States (35.7% versus 18.2%, ASD 0.40) and urban/metropolitan areas (83.9% versus 76.8%, ASD 0.18). There were also differences in hospital-level characteristics between cohorts. However, in-hospital outcomes were similar (mortality, 23.3% versus 20.1%, ASD 0.08; home discharge, 45.5% versus 50.7%, ASD 0.10; skilled nursing facility discharge, 24.4% versus 22.2%, ASD 0.05). Conclusions Linkage of the AHA Registry with external data sources such as Medicare FFS claims creates a unique and generalizable resource to evaluate long-term health outcomes after COVID-19 hospitalization.

Indexed as

Cardiovascular DiseasesCOVID-19AgedAmerican Heart AssociationFemaleHumansMedicareRegistriesUnited Statescardiovascular diseasesCOVID‐19fee‐for‐servicemedicaremortalitypostdischarge outcomesreadmissions

Identifiers

PMID36102226
PMCPMC9683646

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.