Evidence map›Paper›PMID 36101897›Full record

ArticleSynthetic and systems biotechnology2022

Norditerpenoids biosynthesized by variediene synthase-associated P450 machinery along with modifications by the host cell

Lan Jiang, Kangjie Lv, Guoliang Zhu, Zhi Lin, Xue Zhang, Cuiping Xing, Huanting Yang, Weiyan Zhang, Zhixin Wang, Chengwei Liu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Synthetic and systems biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Lan JiangState Key Laboratory of Bioreactor Engineering, East China University of Science of Technology, Shanghai, China.
Kangjie LvState Key Laboratory of Bioreactor Engineering, East China University of Science of Technology, Shanghai, China.
Guoliang ZhuState Key Laboratory of Bioreactor Engineering, East China University of Science of Technology, Shanghai, China.
Zhi LinState Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Xue ZhangState Key Laboratory of Bioreactor Engineering, East China University of Science of Technology, Shanghai, China.
Cuiping XingState Key Laboratory of Bioreactor Engineering, East China University of Science of Technology, Shanghai, China.
Huanting YangState Key Laboratory of Bioreactor Engineering, East China University of Science of Technology, Shanghai, China.
Weiyan ZhangState Key Laboratory of Bioreactor Engineering, East China University of Science of Technology, Shanghai, China.
Zhixin WangState Key Laboratory of Bioreactor Engineering, East China University of Science of Technology, Shanghai, China.
Chengwei LiuKey Laboratory of Saline-alkali Vegetation Ecology Restoration, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin, China.
Xudong QuState Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Tom HsiangSchool of Environmental Sciences, University of Guelph, 50 Stone Road East, Guelph, Ontario, Canada.
Lixin ZhangState Key Laboratory of Bioreactor Engineering, East China University of Science of Technology, Shanghai, China.
Xueting LiuState Key Laboratory of Bioreactor Engineering, East China University of Science of Technology, Shanghai, China.
East China University of Science and Technology · CNShanghai Jiao Tong University · CNNortheast Forestry University · CNUniversity of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The chemical diversity of terpenoids is typically established by terpene synthase-catalyzed cyclization and diversified by post-tailoring modifications. Fungal bifunctional terpene synthase (BFTS) associated P450 enzymes have shown significant catalytic potentials through the development of various new terpenoids with different biological activities. This study discovered the BFTS and its related gene cluster from the plant endophytic fungus

Indexed as

Aspergillus oryzaeBifunctional terpene synthasesCytochrome P450Heterologous expressionNorditerpenoids

Identifiers

PMID36101897
PMCPMC9440366
OpenAlexW4292764257

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.