Evidence map›Paper›PMID 36101821›Full record

ArticleJIMD reports2022

Glutamine energy substrate anaplerosis increases bone density in the Pah

Steven F Dobrowolski, Yu Leng Phua, Irina L Tourkova, Cayla Sudano, Jerry Vockley, Quitterie C Larrouture, Harry C Blair

Open access · goldAbstract read
In one paragraph

Article in JIMD reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Creatine energy substrate increases bone density in the PahMolecular genetics and metabolism reports · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Steven F DobrowolskiDepartment of Pathology University of Pittsburgh, School of Medicine Pittsburgh Pennsylvania USA.ORCID https://orcid.org/0000-0001-5810-4863
Yu Leng PhuaDivision of Medical Genetics and Genomics Children's Hospital of Pittsburgh Pittsburgh Pennsylvania USA.
Irina L TourkovaDepartment of Pathology University of Pittsburgh, School of Medicine Pittsburgh Pennsylvania USA.
Cayla SudanoDepartment of Pathology University of Pittsburgh, School of Medicine Pittsburgh Pennsylvania USA.
Jerry VockleyDivision of Medical Genetics and Genomics Children's Hospital of Pittsburgh Pittsburgh Pennsylvania USA.
Quitterie C LarroutureDepartment of Pathology University of Pittsburgh, School of Medicine Pittsburgh Pennsylvania USA.
Harry C BlairDepartment of Pathology University of Pittsburgh, School of Medicine Pittsburgh Pennsylvania USA.
University of Pittsburgh · USChildren's Hospital of Pittsburgh · US

Funding

Epithelial Osteoblast Function: The Role of Acid TransportR01AR076146 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BLAIR, HARRY COLBERT, NELSON, DEBORAH J. · 2020 to 2024
$2.6M
BLRD VA I01 BX002490NIAMS NIH HHS R01 AR076146
6 · The paper itself

Abstract

Osteopenia is an under-investigated clinical presentation of phenylalanine hydroxylase (PAH)-deficient phenylketonuria (PKU). While osteopenia is not fully penetrant in human PKU, the Pah

Indexed as

glutamineosteopeniaoxidative phosphorylationPahenu2phenylketonuria

Identifiers

PMID36101821
PMCPMC9458609
OpenAlexW4284894841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.