ArticleBJR case reports2022
SpaceOAR hydrogel spacer in interstitial brachytherapy for intrapelvic recurrent endometrial cancer.
Article in BJR case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 4 citations in OpenAlex.
- Stabilised Hyaluronic Acid Gel Rectal Spacers in MRI-Guided Brachytherapy for Gynaecological Cancers: A Prospective Feasibility Study.Journal of medical radiation sciences · 2026Article
- From mechanism to applications: Advanced microneedles for clinical medicine.Bioactive materials · 2025Review
- Protecting organs-at-risk in cancer therapies through temporary organ displacement: a comprehensive review.Oncology reviews · 2025Review
- Injectable bio-absorbable spacers in brachytherapy for gynecological cancers: A scoping review.Journal of contemporary brachytherapy · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: We report the use of SpaceOAR hydrogel spacer in interstitial brachytherapy (ISBT) for a patient with intrapelvic recurrent endometrial cancer (EC). Methods and materials: A 59-year-old female patient was diagnosed with intrapelvic recurrence of EC after a definitive surgery. Despite administration of adjuvant chemotherapy, the recurrent tumour in the right para-rectal fossa increased in size. Salvage radiotherapy, including external beam radiotherapy followed by ISBT boost, was planned. We planned to inject SpaceOAR between the tumour and rectum to reduce the rectal dose in ISBT; transrectal ultrasound-guided SpaceOAR injection was performed using needle applicator insertion. This was followed by computed tomography-based image-guided brachytherapy. Results: The use of SpaceOAR allowed us to achieved both a higher dose for the clinical target volume and a lower dose for the rectum. Furthermore, no ISBT-related complications or acute toxicities were observed. Conclusions: The preliminary results suggest that SpaceOAR could be effective in increasing the efficacy of ISBT for intrapelvic recurrent EC, while reducing the associated complications.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.