Evidence map›Paper›PMID 36101573›Full record

ArticlePublic health in practice (Oxford, England)2021

Loss to follow up after pregnancy among mothers enrolled on the option B+ program in Uganda.

Yerusa Kiirya, Philippa Musoke, Gloria Adobea Odei Obeng-Amoako, Joan Kalyango

Abstract read
In one paragraph

Article in Public health in practice (Oxford, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yerusa KiiryaMakerere University School of Medicine Clinical Epidemiology Unit Uganda, Uganda.
Philippa MusokeMakerere University, Department of Paediatrics and Child Health, Uganda.
Gloria Adobea Odei Obeng-AmoakoMakerere University School of Medicine Clinical Epidemiology Unit Uganda, Uganda.
Joan KalyangoMakerere University School of Medicine Clinical Epidemiology Unit Uganda, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Option-B+ programs in Uganda have reported high levels of loss to follow up (LTFU) after cessation of breastfeeding, and this remains unknown beyond this period. In this study, we assessed the incidence and factors associated with LTFU two to four years after delivery among Option-B+ mothers. Study design: Retrospective cohort Methods: We reviewed files of 452 mothers who enrolled on Option-B+ between January 1st, 2013 and December 31st, 2014 ​at Kisenyi Health Centre IV in Kampala district. We assessed factors associated with LTFU using Cox proportional hazards regression. We also explored the reasons for LTFU using three focus group discussions, five in-depth and three key informant interviews. Results: Of the 452 mothers, 131(29%) were LTFU after delivery. The incidence of LTFU after delivery was 17/1000 person months (95% CI, 14-30/1000) with a median follow up of 32 months. The risk of LTFU was higher among mothers who started ART on the day they tested HIV positive (aHR ​= ​1.66, 95% CI; 1.25-2.20, p-value< 0.001). Reasons for LFTU included transport costs, stigma, poor human resource policies and non-disclosure. Conclusion: LTFU after delivery among Option-B+ mothers is higher than the global target of 15%. ART initiation on the day a mother tests positive increases the risk of LTFU. The major reasons for LTFU were stigma and non-disclosure. To reduce the risk of LTFU, we recommend approaches that encourage disclosure to sexual partners and ongoing specific support to mothers who are initiated on ART-the day of positive test.

Indexed as

After deliveryFGDs, Focus Group DiscussionsIDIs, In-depth InterviewsKIIs, Key Informant InterviewsLoss to follow upLTFU, Lost to Follow up and pmo-person monthsOption-B+ mothers

Identifiers

PMID36101573
PMCPMC9461603

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.