Evidence map›Paper›PMID 36101528›Full record

ReviewThe Malaysian journal of medical sciences : MJMS2022

Antimicrobial Effects of Tetraspanins: A New Turnabout in Treatment of Microorganisms.

Khairiyah Murad, Sharaniza Ab Rahim, Hassanain Al-Talib

Abstract readReview
In one paragraph

Review in The Malaysian journal of medical sciences : MJMS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Khairiyah MuradInstitute for Medical and Molecular Biotechnology (IMMB), Universiti Teknologi MARA, Selangor, Malaysia.
Sharaniza Ab RahimDepartment of Biochemistry and Molecular Medicine, Faculty of Medicine, Universiti Teknologi MARA, Selangor, Malaysia.
Hassanain Al-TalibDepartment of Medical Microbiology and Parasitology, Faculty of Medicine, Universiti Teknologi MARA, Selangor, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tetraspanins, a transmembrane protein is a 'molecular organiser' with diverse functions that promote a network of signalling involved in the cellular and pathological processes. Tetraspanins-enriched microdomains (TEMs) are the crucial feature for the protein-protein interactions in the cell membrane and are vulnerable to pathogens exploitation. Targetting the tetraspanins has shown to be effective against microbial infections although more research is needed to be performed. This article will review previous evidence that has successfully demonstrated the potential mechanism to target tetraspanins as an antimicrobial agent.

Indexed as

antibodiesantimicrobialbacterial adhesionblocking peptidetetraspanins

Identifiers

PMID36101528
PMCPMC9438860

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.