Evidence map›Paper›PMID 36101488›Full record

Observational studyBrain injury2022

Effects of inpatient rehabilitation after acute care on functional and quality-of-life outcomes in children with severe traumatic brain injury.

Shiyao Gao, Amery Treble-Barna, Anthony Fabio, M Kathleen Kelly, Sue R Beers, Bedda L Rosario, Michael J Bell, Stephen R Wisniewski

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Brain injury, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Shiyao GaoDepartment of Epidemiology, Epidemiology Data Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Amery Treble-BarnaDepartment of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Anthony FabioDepartment of Epidemiology, Epidemiology Data Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
M Kathleen KellyDepartment of Physical Therapy, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Sue R BeersDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Bedda L RosarioDepartment of Epidemiology, Epidemiology Data Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Michael J BellDepartment of Pediatrics, Division of Critical Care Medicine, Washington, DC, USA.
Stephen R WisniewskiDepartment of Epidemiology, Epidemiology Data Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
University of Pittsburgh · US

Funding

Multiple Medical Therapies for Pediatric TBI; Comparative Effectiveness ApproachU01NS081041 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BELL, MICHAEL J, WISNIEWSKI, STEPHEN R · 2013 to 2017
$15.9M
NINDS NIH HHS U01 NS081041
6 · The paper itself

Abstract

objectiveFew studies have assessed the effectiveness of the rehabilitation process in children surviving severe traumatic brain injury (TBI). We evaluated whether receiving inpatient rehabilitation after acute hospitalization was associated with better functional outcomes compared to receiving only non-inpatient rehabilitation in children with severe TBI and explored an effect modification for Glasgow Coma Scale (GCS) score at hospital discharge.

methodsWe included 254 children who received rehabilitation following severe TBI from a multinational observational study. The Pediatric Glasgow Outcome Scale - Extended (GOS-E Peds), parent/guardian-reported and child-reported Pediatric Quality of Life Inventory (PedsQL) at 12 months post-injury were assessed and described using summary statistics. Unadjusted and propensity score-weighted linear/ordinal logistic regression modeling were also performed.

results180 children received inpatient rehabilitation and 74 children received only non-inpatient rehabilitation after acute hospitalization. Among children with a GCS<13 at discharge, those receiving inpatient rehabilitation had a more favorable GOS-E Peds score (OR = 0.12, p = 0.045). However, no such association was observed in children with a higher GCS. We found no differences in PedsQL scores between rehabilitation groups.

conclusionsFuture studies are warranted to confirm the benefits of inpatient rehabilitation for children with more severely impaired consciousness when medically stable.

Indexed as

Brain InjuriesBrain Injuries, TraumaticChildGlasgow Coma ScaleGlasgow Outcome ScaleHumansQuality of LifeChildGOS-E pedshealth related quality of liferehabilitationsevere traumatic brain injury

Identifiers

PMID36101488
PMCPMC9890641
OpenAlexW4295754074

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.