Evidence map›Paper›PMID 36101412›Full record

ArticleBiology2022

The Effect of Traumatic Brain Injury on Sleep Architecture and Circadian Rhythms in Mice-A Comparison of High-Frequency Head Impact and Controlled Cortical Injury.

Holly T Korthas, Bevan S Main, Alex C Harvey, Ruchelle G Buenaventura, Evan Wicker, Patrick A Forcelli, Mark P Burns

Open access · goldAbstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

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  7. Traumatic brain injury-induced disruption of the circadian clock.Journal of molecular medicine (Berlin, Germany) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Holly T KorthasInterdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC 20057, USA.
Bevan S MainDepartment of Neuroscience, Georgetown University Medical Center, Washington, DC 20057, USA.
Alex C HarveyDepartment of Neuroscience, Georgetown University Medical Center, Washington, DC 20057, USA.
Ruchelle G BuenaventuraDepartment of Neuroscience, Georgetown University Medical Center, Washington, DC 20057, USA.
Evan WickerDepartment of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC 20057, USA.
Patrick A ForcelliInterdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC 20057, USA.
Mark P BurnsInterdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC 20057, USA.ORCID 0000-0003-4750-2000
Georgetown University · US

Funding

Training in Neural Injury &PlasticityT32NS041218 · NINDS · GEORGETOWN UNIVERSITY · PI MARK P BURNS, Kathleen Anne Maguire-Zeiss · 2001 to 2026
$3.5M
Tau-independent effects of high frequency head impact on cognition and neurobehaviorR01NS107370 · NINDS · GEORGETOWN UNIVERSITY · PI BURNS, MARK P · 2018 to 2022
$1.9M
Recovering amnestic memories from the repeat head impact brainRF1NS121316 · NINDS · GEORGETOWN UNIVERSITY · PI BURNS, MARK P · 2021 to 2021
$1.0M
Recovering amnestic memories from the repeat head impact brainR01NS121316 · NINDS · GEORGETOWN UNIVERSITY · PI BURNS, MARK P · 2024 to 2025
$684k
NINDS NIH HHS R01 NS107370NINDS NIH HHS R01NS107370NINDS NIH HHS R01 NS121316NINDS NIH HHS RF1 NS121316NINDS NIH HHS RF1NS121316NINDS NIH HHS T32 NS041218NINDS NIH HHS T32NS041218
6 · The paper itself

Abstract

Traumatic brain injury (TBI) is a significant risk factor for the development of sleep and circadian rhythm impairments. In this study we compare the circadian rhythms and sleep patterns in the high-frequency head impact (HFHI) and controlled cortical impact (CCI) mouse models of TBI. These mouse models have different injury mechanisms key differences of pathology in brain regions controlling circadian rhythms and EEG wave generation. We found that both HFHI and CCI caused dysregulation in the diurnal expression of core circadian genes (

Indexed as

circadian rhythmconcussionmild TBI (mTBI)sleeptraumatic brain injury (TBI)

Identifiers

PMID36101412
PMCPMC9312487
OpenAlexW4284959866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.