ArticleBiology2022
Ontogenetic Patterning of Human Subchondral Bone Microarchitecture in the Proximal Tibia.
Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Mesh-based detailed skeletal models for the ICRP reference pediatric individuals: development and dosimetric implications.Physics in medicine and biology · 2026Article
- Mineralized area of the human rib cross-sections from early puberty until adulthood.Anatomical record (Hoboken, N.J. : 2007) · 2026Article
- Trabecular Bone Ontogeny of the Human Distal Tibia.American journal of biological anthropology · 2025Article
- The developing juvenile talus: Radiographic identification of distinct ontogenetic phases and structural trajectories.Journal of anatomy · 2024Article
- Identification of functionally related adaptations in the trabecular network of the proximal femur and tibia of a bipedally trained Japanese macaque.Anthropological science : journal of the Anthropological Society of Nippon = Jinruigaku zasshi · 2024Article
- The developing juvenile distal tibia: Radiographic identification of distinct ontogenetic phases and structural trajectories.Journal of anatomy · 2023Article
- Development of a Bionic Tube with High Bending-Stiffness Properties Based on Human Tibiofibular Shapes.Biomimetics (Basel, Switzerland) · 2023Article
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Authors and funding
4 authors.
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Abstract
High-resolution computed tomography images were acquired for 31 proximal human tibiae, age 8 to 37.5 years, from Norris Farms #36 cemetery site (A.D. 1300). Morphometric analysis of subchondral cortical and trabecular bone architecture was performed between and within the tibial condyles. Kruskal−Wallis and Wilcoxon signed-rank tests were used to examine the association between region, age, body mass, and each morphometric parameter. The findings indicate that age-related changes in mechanical loading have varied effects on subchondral bone morphology. With age, trabecular microstructure increased in bone volume fraction (p = 0.033) and degree of anisotropy (p = 0.012), and decreased in connectivity density (p = 0.001). In the subchondral cortical plate, there was an increase in thickness (p < 0.001). When comparing condylar regions, only degree of anisotropy differed (p = 0.004) between the medial and lateral condyles. Trabeculae in the medial condyle were more anisotropic than in the lateral region. This research represents an innovative approach to quantifying both cortical and trabecular subchondral bone microarchitecture in archaeological remains.
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