Evidence map›Paper›PMID 36101370›Full record

ArticleBiology2022

Neuronal Depolarization Induced RNA m

Xiguang Xu, Zachary Johnson, Hehuang Xie

Open access · goldAbstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Xiguang XuEpigenomics and Computational Biology Lab, Fralin Life Sciences Institute, Virginia Tech, Blacksburg, VA 24061, USA.
Zachary JohnsonEpigenomics and Computational Biology Lab, Fralin Life Sciences Institute, Virginia Tech, Blacksburg, VA 24061, USA.ORCID 0000-0001-5374-3244
Hehuang XieEpigenomics and Computational Biology Lab, Fralin Life Sciences Institute, Virginia Tech, Blacksburg, VA 24061, USA.ORCID 0000-0001-5739-1653
Virginia Tech · USVirginia–Maryland College of Veterinary Medicine · US

Funding

Functional RNA Modifications, Micronutrient Exposure, Developmental DisabilitiesR01ES031521 · NIEHS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI WANG, XIAOBIN, XIE, HEHUANG · 2020 to 2024
$1.9M
The epigenetic role of EGR1 during postnatal brain development and in neuronal activityR01NS094574 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI XIE, HEHUANG · 2016 to 2020
$1.7M
Exploring epigenetic regulation of memory extinctionR21MH120498 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI JAROME, TIMOTHY JOSEPH, XIE, HEHUANG · 2020 to 2020
$419k
National Institute of Health ES031521National Institute of Health MH120498National Science Foundation NSF1922428NIEHS NIH HHS R01 ES031521NIH HHS NS094574NIMH NIH HHS R21 MH120498NINDS NIH HHS R01 NS094574
6 · The paper itself

Abstract

Neuronal activity is accomplished via substantial changes in gene expression, which may be accompanied by post-transcriptional modifications including RNA cytosine-5 methylation (m

Indexed as

gene expressionneuronal depolarizationRNA bisulfite sequencingRNA cytosine-5 methylationRNA-seq

Identifiers

PMID36101370
PMCPMC9311806
OpenAlexW4283720269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.