Evidence map›Paper›PMID 36101353›Full record

ReviewBiology2022

Molecular Mechanisms and Key Processes in Interstitial, Hemorrhagic and Radiation Cystitis.

Clément Brossard, Anne-Charlotte Lefranc, Anne-Laure Pouliet, Jean-Marc Simon, Marc Benderitter, Fabien Milliat, Alain Chapel

Open access · goldAbstract readReview
In one paragraph

Review in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Clément BrossardLaboratoire de Radiobiologie des Expositions Médicales (LRMED), Service de Recherche en Radiobiologie et en Médecine Régénérative (SERAMED), Institut de Radioprotection et de Sûreté Nucléaire (IRSN), 92260 Fontenay-aux-Roses, France.
Anne-Charlotte LefrancLaboratoire de Radiobiologie des Expositions Médicales (LRMED), Service de Recherche en Radiobiologie et en Médecine Régénérative (SERAMED), Institut de Radioprotection et de Sûreté Nucléaire (IRSN), 92260 Fontenay-aux-Roses, France.
Anne-Laure PoulietLaboratoire de Radiobiologie des Expositions Médicales (LRMED), Service de Recherche en Radiobiologie et en Médecine Régénérative (SERAMED), Institut de Radioprotection et de Sûreté Nucléaire (IRSN), 92260 Fontenay-aux-Roses, France.
Jean-Marc SimonRadiotherapy Oncology Department, Hôpital Universitaire Pitié-Salpêtrière, 47-83 Boulevard de l'Hôpital, CEDEX 13, 75651 Paris, France.
Marc BenderitterLaboratoire de Radiobiologie des Expositions Médicales (LRMED), Service de Recherche en Radiobiologie et en Médecine Régénérative (SERAMED), Institut de Radioprotection et de Sûreté Nucléaire (IRSN), 92260 Fontenay-aux-Roses, France.
Fabien MilliatLaboratoire de Radiobiologie des Expositions Médicales (LRMED), Service de Recherche en Radiobiologie et en Médecine Régénérative (SERAMED), Institut de Radioprotection et de Sûreté Nucléaire (IRSN), 92260 Fontenay-aux-Roses, France.
Alain ChapelLaboratoire de Radiobiologie des Expositions Médicales (LRMED), Service de Recherche en Radiobiologie et en Médecine Régénérative (SERAMED), Institut de Radioprotection et de Sûreté Nucléaire (IRSN), 92260 Fontenay-aux-Roses, France.ORCID 0000-0002-4687-4120
Institut de Radioprotection et de Sûreté Nucléaire · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystitis is a bladder disease with a high rate of prevalence in the world population. This report focuses on Interstitial Cystitis (IC), Hemorrhagic Cystitis (HC) and Chronic Radiation Cystitis. These pathologies have different etiologies, but they share common symptoms, for instance, pain, bleeding, and a contracted bladder. Overall, treatments are quite similar for abacterial cystitis, and include bladder epithelium protective or anti-inflammatory agents, alleviating pain and reducing bleeding. This review summarizes the mechanisms that the pathologies have in common, for instance, bladder dysfunction and inflammation. Conversely, some mechanisms have been described as present in only one pathology, such as neural regulation. Based on these specificities, we propose identifying a mechanism that could be common to all the above-mentioned pathologies.

Indexed as

bleedingcancercystitisinflammationmechanismpelvic radiation diseaseradiation

Identifiers

PMID36101353
PMCPMC9311586
OpenAlexW4283642379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.