Evidence map›Paper›PMID 36100948›Full record

ArticleJournal of animal science and biotechnology2022

Stimbiotic supplementation modulated intestinal inflammatory response and improved boilers performance in an experimentally-induced necrotic enteritis infection model.

Ji Hwan Lee, Byongkon Lee, Xavière Rousseau, Gilson A Gomes, Han Jin Oh, Yong Ju Kim, Se Yeon Chang, Jae Woo An, Young Bin Go, Dong Cheol Song and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of animal science and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
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  4. Hematological and Biochemical Parameters of European Quails (Animals : an open access journal from MDPI · 2025
    Article
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  9. Review
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  12. Effects ofFrontiers in physiology · 2023
    Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Ji Hwan LeeDepartment of Animal Science, Chungbuk National University, Cheongju, 28644, South Korea.
Byongkon LeeDepartment of Animal Science, Chungbuk National University, Cheongju, 28644, South Korea.
Xavière RousseauAB Vista, Marlborough, Wiltshire, UK.
Gilson A GomesAB Vista, Marlborough, Wiltshire, UK.
Han Jin OhDepartment of Animal Science, Chungbuk National University, Cheongju, 28644, South Korea.
Yong Ju KimDepartment of Animal Science, Chungbuk National University, Cheongju, 28644, South Korea.
Se Yeon ChangDepartment of Animal Science, Chungbuk National University, Cheongju, 28644, South Korea.
Jae Woo AnDepartment of Animal Science, Chungbuk National University, Cheongju, 28644, South Korea.
Young Bin GoDepartment of Animal Science, Chungbuk National University, Cheongju, 28644, South Korea.
Dong Cheol SongDepartment of Animal Science, Chungbuk National University, Cheongju, 28644, South Korea.
Hyun Ah ChoDepartment of Animal Science, Chungbuk National University, Cheongju, 28644, South Korea.
Jin Ho ChoDepartment of Animal Science, Chungbuk National University, Cheongju, 28644, South Korea. jinhcho@chungbuk.ac.kr.ORCID http://orcid.org/0000-0001-7151-0778
Chungbuk National University · KRAB Vista (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTwo experiments were conducted to establish an optimal NE challenge model and evaluate the efficacy of stimbiotic (STB) supplementation in necrotic enteritis (NE) challenged broilers. In Exp. 1, a total of 120 Arbor Acres (AA) broilers (45.0 ± 0.21 g) were randomly assigned to 6 treatments in a 3 × 2 factorial arrangement. Vaccine treatments included non-challenge (0), × 10 the recommended dose (× 10) or × 20 the recommended dose (× 20) by the manufacturer. Clostridium perfringens (CP) treatments were non-challenge (No) or 3 mL of 2.2 × 10

resultsIn Exp. 1, CP and vaccine challenge decreased (P < 0.05) body weight (BW), body weight gain (BWG) and feed intake (FI), and increased (P < 0.05) the number of broilers with diarrhea and intestinal lesions. The oral administration of × 20 recommended dose of vaccines coupled with 3 mL of 2.2 × 10

conclusionOverall, these results indicate that STB supplementation was able to reduce the inflammatory response and improve the performance of NE challenged birds, and the supplementation of STB alone was as effective as a typical commercial blend containing a number of other additives.

Indexed as

Broiler chickenClostridium perfringensNecrotic enteritisXylanseXylooligosaccharide

Identifiers

PMID36100948
PMCPMC9472449
OpenAlexW4295756813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.