ArticleScientific reports2022
Towards robust in vivo quantification of oscillating biomagnetic fields using Rotary Excitation based MRI.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 7 citations in OpenAlex.
- An Open-Source, Reproducible MRI Data Acquisition and Reconstruction Workflow Using Pulseq: Multi-Site and Cross-Vendor Validation.Magnetic resonance in medicine · 2026Article
- Increasing the measurable frequency range of magnetic field oscillations with off-resonance spin-lock preparation pulses.Magnetic resonance in medicine · 2026Article
- Quadruple-refocused spin-locking: A robust method for high-amplitude TMagnetic resonance in medicine · 2025Article
- Stimulus-induced rotary saturation imaging of visually evoked response: A pilot study.NMR in biomedicine · 2025Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spin-lock based functional magnetic resonance imaging (fMRI) has the potential for direct spatially-resolved detection of neuronal activity and thus may represent an important step for basic research in neuroscience. In this work, the corresponding fundamental effect of Rotary EXcitation (REX) is investigated both in simulations as well as in phantom and in vivo experiments. An empirical law for predicting optimal spin-lock pulse durations for maximum magnetic field sensitivity was found. Experimental conditions were established that allow robust detection of ultra-weak magnetic field oscillations with simultaneous compensation of static field inhomogeneities. Furthermore, this work presents a novel concept for the emulation of brain activity utilizing the built-in MRI gradient system, which allows REX sequences to be validated in vivo under controlled and reproducible conditions. Via transmission of Rotary EXcitation (tREX), we successfully detected magnetic field oscillations in the lower nano-Tesla range in brain tissue. Moreover, tREX paves the way for the quantification of biomagnetic fields.
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