Evidence map›Paper›PMID 36100615›Full record

ArticleScientific reports2022

Transfontanelle photoacoustic imaging for in-vivo cerebral oxygenation measurement.

Rayyan Manwar, Laura S McGuire, Md Tarikul Islam, Anthony Shoo, Fady T Charbel, De-Ann M Pillers, Kamran Avanaki

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Photoacoustic imaging of intestinal physiological biomarkers in infants and children.medRxiv : the preprint server for health sciences · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Rayyan ManwarRichard and Loan Hill Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA.
Laura S McGuireDepartment of Neurological Surgery, University of Illinois at Chicago - College of Medicine, Chicago, IL, USA.
Md Tarikul IslamRichard and Loan Hill Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA.
Anthony ShooSection of Neonatology, Department of Pediatrics, UIHealth Children's Hospital of the University of Illinois at Chicago, Chicago, IL, USA.
Fady T CharbelDepartment of Neurological Surgery, University of Illinois at Chicago - College of Medicine, Chicago, IL, USA.
De-Ann M PillersSection of Neonatology, Department of Pediatrics, UIHealth Children's Hospital of the University of Illinois at Chicago, Chicago, IL, USA.
Kamran AvanakiRichard and Loan Hill Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA. avanaki@uic.edu.
University of Illinois Chicago · USNeurological Surgery · USComer Children's Hospital · USUniversity of Illinois Hospital & Health Sciences System · US

Funding

Transfontanelle photoacoustic imaging to study pathophysiology of neonatal braininjuryR01EB027769 · NIBIB · WAYNE STATE UNIVERSITY · PI AVANAKI, KAMRAN · 2019 to 2023
$1.7M
3D neonatal Photoacoustic Tomography (3D-nPAT) to detect Hypoxic-Ischemicbrain injury in preterm neonatesR01EB028661 · NIBIB · WAYNE STATE UNIVERSITY · PI AVANAKI, KAMRAN · 2019 to 2019
$725k
In vivo photoacoustic imaging of prefrontal cortex in rats undergoing fentanyl self-administrationR21DA052657 · NIDA · WAYNE STATE UNIVERSITY · PI AVANAKI, KAMRAN, PERRINE, SHANE ALAN · 2021 to 2022
$415k
NIBIB NIH HHS R01 EB027769NIBIB NIH HHS R01 EB028661NIDA NIH HHS R21 DA052657NIH HHS R01EB027769-01, R01EB028661-01, R21 DA052657
6 · The paper itself

Abstract

The capability of photoacoustic (PA) imaging to measure oxygen saturation through a fontanelle has been demonstrated in large animals in-vivo. We called this method, transfontanelle photoacoustic imaging (TFPAI). A surgically induced 2.5 cm diameter cranial window was created in an adult sheep skull to model the human anterior fontanelle. The performance of the TFPAI has been evaluated by comparing the PA-based predicted results against the gold standard of blood gas analyzer measurements.

Indexed as

Photoacoustic TechniquesAdultAnimalsBlood Gas AnalysisDiagnostic ImagingHumansOxygenSheepOxygen

Identifiers

PMID36100615
PMCPMC9470703
OpenAlexW4295754512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.