Evidence map›Paper›PMID 36100083›Full record

ArticleJournal of endodontics2022

Minimal Detectable Width of Tooth Fractures Using Magnetic Resonance Imaging and Method to Measure.

Beth R Groenke, Djaudat Idiyatullin, Laurence Gaalaas, Ashley Petersen, Hooi Pin Chew, Alan Law, Brian Barsness, Mathew Royal, Ronald Ordinola-Zapata, Alex Fok and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of endodontics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Intraoral Coil Arrays for Single-Tooth Dental MRI.Magnetic resonance in medicine · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Beth R GroenkeDivision of TMD and Orofacial Pain, School of Dentistry, University of Minnesota, Minneapolis, Minnesota. Electronic address: groenke@umn.edu.
Djaudat IdiyatullinThe Center for Magnetic Resonance Research, Minneapolis, Minnesota.
Laurence GaalaasDepartment of Radiology, School of Dentistry, University of Minnesota, Minneapolis, Minnesota.
Ashley PetersenDivision of Biostatistics, University of Minnesota, Minneapolis, Minnesota.
Hooi Pin ChewDivision of Biomaterials, University of Minnesota, Minneapolis, Minnesota.
Alan LawPrivate Practice, The Dental Specialists, Woodbury, Minnesota.
Brian BarsnessPrivate Practice, HealthPartners, St Paul, Minnesota.
Mathew RoyalPrivate Practice, HealthPartners, St Paul, Minnesota.
Ronald Ordinola-ZapataDivision of Endodontics, School of Dentistry, University of Minnesota, Minneapolis, Minnesota.
Alex FokMinnesota Dental Research Center for Biomaterials and Biomechanics, Minneapolis, Minnesota.
Wondwosen AregawiMinnesota Dental Research Center for Biomaterials and Biomechanics, Minneapolis, Minnesota.
Donald R NixdorfDivision of TMD and Orofacial Pain, School of Dentistry, University of Minnesota, Minneapolis, Minnesota; Departments of Radiology & Neurology, Medical School, University of Minnesota, Minneapolis, Minnesota.
University of Minnesota · USHealthPartners · USMidwest Orthopaedic Research Foundation · USResonance Research (United States) · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger · 2019 to 2026
$11.7M
4 Tesla Human MRI/MRS Console UpgradeS10RR023730 · NCRR · UNIVERSITY OF MINNESOTA · PI GARWOOD, MICHAEL G · 2007 to 2007
$500k
NCATS NIH HHS UL1 TR002494NCRR NIH HHS S10 RR023730NIBIB NIH HHS P41 EB027061
6 · The paper itself

Abstract

introductionVertical root fracture (VRF) in root canal-treated (RCT) teeth is a common cause of pain, bone resorption, and tooth loss. VRF is also difficult to diagnose and measure. Magnetic resonance imaging (MRI) has the potential to identify VRF due to beneficial partial volume averaging, without using ionizing radiation. This investigation aimed to describe the narrowest VRFs detectable based on MRI, using micro-computed tomography (microCT) as the reference standard and proposes a method using profile integrals to measure the widths of small VRFs.

methodsVRFs were induced in 62 RCT tooth root samples. All samples were imaged in a phantom using MRI and reference imaging was obtained using microCT. The stacks of 3-dimensional axial MRIs were assessed by 3 board-certified endodontists. Evaluators determined the most coronal slice within the stack that was discernible as the extent of the VRF. This slice was measured on correlated microCT sections to determine the minimum VRF width (μm) detectable using a profile integral-based method to measure small fractures and negate the effects of the point spread function.

resultsUsing profile integrals to measure VRF width was repeatable and resulted in estimates that were on average 1 μm smaller than known reference widths. Adjusted median VRF width detected using MRI was 45 μm (first quartile: 26 μm, third quartile: 64 μm).

conclusionUsing profile integrals is a valid way to estimate small VRF width. The MRI approach demonstrated ability to repeatedly detect VRFs as small as 26 μm.

Indexed as

Tooth FracturesTooth, NonvitalCone-Beam Computed TomographyHumansMagnetic Resonance ImagingRoot Canal TherapyTooth RootDentistrydiagnosismicroCTMRIpainroot canalSWIFT

Identifiers

PMID36100083
PMCPMC9704057
OpenAlexW4295242442

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.