Evidence map›Paper›PMID 36099186›Full record

ArticleJournal of dietary supplements2023

Integrated Profiling of Gram-Positive and Gram-Negative Probiotic Genomes, Proteomes and Metabolomes Revealed Small Molecules with Differential Growth Inhibition of Antimicrobial-Resistant Pathogens.

Petronella R Hove, Nora Jean Nealon, Siu Hung Joshua Chan, Shea M Boyer, Hannah B Haberecht, Elizabeth P Ryan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of dietary supplements, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Microorganisms · 2023
    Article
  4. Advances inMaterials today. Bio · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Petronella R HoveDepartment of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.ORCID 0000-0002-4779-5264
Nora Jean NealonDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA.ORCID 0000-0002-8146-5664
Siu Hung Joshua ChanDepartment of Chemical and Biological Engineering, Colorado State University, Fort Collins, CO, USA.ORCID 0000-0002-7707-656X
Shea M BoyerDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA.ORCID 0000-0003-2994-645X
Hannah B HaberechtDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA.ORCID 0000-0001-8794-9101
Elizabeth P RyanDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA.ORCID 0000-0002-1577-0919
Colorado State University · US

Funding

Rice Bran Microbial Metabolism for Colon ChemopreventionR01CA201112 · NCI · COLORADO STATE UNIVERSITY · PI RAINA, KOMAL, RYAN, ELIZABETH P · 2016 to 2020
$1.9M
Veterinary Pre-Doctoral Research Scholars ProgramT32OD012201 · OD · COLORADO STATE UNIVERSITY · PI VANDEWOUDE, SUE · 2013 to 2019
$795k
Rice bran in ready-to-use therapeutic foods for microbiota-targeted treatment of childhood malnutritionR21HD113211 · NICHD · COLORADO STATE UNIVERSITY · PI RYAN, ELIZABETH P · 2023 to 2023
$417k
NCI NIH HHS R01 CA201112NICHD NIH HHS R21 HD113211NIH HHS T32 OD012201
6 · The paper itself

Abstract

Probiotics produce small molecules that may serve as alternatives to conventional antibiotics by suppressing growth of antimicrobial resistant (AMR) pathogens. The objective of this study was to identify and examine antimicrobials produced and secreted by probiotics using 'omics' profiling with computer-based metabolic flux analyses. The cell-free supernatant of Gram-positive

Indexed as

Escherichia coliLacticaseibacillus rhamnosusMetabolomeProbioticsDrug Resistance, MicrobialKlebsiella oxytocaProteomeSalmonella typhimuriumProteomeantimicrobial resistancecell free supernatantsgrowth inhibition proteomemetabolomeprobiotics

Identifiers

PMID36099186
PMCPMC10008781
OpenAlexW4295428865

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.