Evidence map›Paper›PMID 36098891›Full record

ArticleBrain topography2022

Levetiracetam Modulates EEG Microstates in Temporal Lobe Epilepsy.

Lorenzo Ricci, Pierpaolo Croce, Patrizia Pulitano, Marilisa Boscarino, Filippo Zappasodi, Flavia Narducci, Jacopo Lanzone, Biagio Sancetta, Oriano Mecarelli, Vincenzo Di Lazzaro and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Brain topography, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

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  15. The effect of acupuncture at theFrontiers in integrative neuroscience · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Lorenzo Ricci *Unit of Neurology, Neurophysiology, Neurobiology, Department of Medicine, University Campus Bio-Medico of Rome, via Álvaro del Portillo, 21, 00128, Rome, Italy.
Pierpaolo Croce *Department of Neuroscience, Imaging and Clinical Sciences, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy. pierpaolo.croce@unich.it.
Patrizia PulitanoDepartment of Human Neurosciences, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Marilisa BoscarinoUnit of Neurology, Neurophysiology, Neurobiology, Department of Medicine, University Campus Bio-Medico of Rome, via Álvaro del Portillo, 21, 00128, Rome, Italy.
Filippo ZappasodiDepartment of Neuroscience, Imaging and Clinical Sciences, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy.
Flavia NarducciUnit of Neurology, Neurophysiology, Neurobiology, Department of Medicine, University Campus Bio-Medico of Rome, via Álvaro del Portillo, 21, 00128, Rome, Italy.
Jacopo LanzoneNeurorehabilitation Department, IRCCS Salvatore Maugeri Foundation, Institute of Milan, Milan, Italy.
Biagio SancettaUnit of Neurology, Neurophysiology, Neurobiology, Department of Medicine, University Campus Bio-Medico of Rome, via Álvaro del Portillo, 21, 00128, Rome, Italy.
Oriano MecarelliDepartment of Human Neurosciences, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Vincenzo Di LazzaroUnit of Neurology, Neurophysiology, Neurobiology, Department of Medicine, University Campus Bio-Medico of Rome, via Álvaro del Portillo, 21, 00128, Rome, Italy.
Mario TombiniUnit of Neurology, Neurophysiology, Neurobiology, Department of Medicine, University Campus Bio-Medico of Rome, via Álvaro del Portillo, 21, 00128, Rome, Italy.
Giovanni AssenzaUnit of Neurology, Neurophysiology, Neurobiology, Department of Medicine, University Campus Bio-Medico of Rome, via Álvaro del Portillo, 21, 00128, Rome, Italy.
Università Campus Bio-Medico · ITFondazione Salvatore Maugeri · ITPoliclinico Umberto I · ITSapienza University of Rome · ITUniversity of Chieti-Pescara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To determine the effects of Levetiracetam (LEV) therapy using EEG microstates analysis in a population of newly diagnosed Temporal Lobe Epilepsy (TLE) patients. We hypothesized that the impact of LEV therapy on the electrical activity of the brain can be globally explored using EEG microstates. Twenty-seven patients with TLE were examined. We performed resting-state microstate EEG analysis and compared microstate metrics between the EEG performed at baseline (EEG

Indexed as

Epilepsy, Temporal LobeBrainBrain MappingElectroencephalographyHumansLevetiracetamLevetiracetamBiomarkersEEGLevetiracetamMicrostatesTemporal lobe epilepsy

Identifiers

PMID36098891
PMCPMC9684258
OpenAlexW4295339412

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.