Evidence map›Paper›PMID 36098685›Full record

ArticleJournal of medicinal chemistry2022

Highly Potent and Selective Dopamine D

Pegi Pavletić, Ana Semeano, Hideaki Yano, Alessandro Bonifazi, Gianfabio Giorgioni, Alessandro Piergentili, Wilma Quaglia, Maria Giovanna Sabbieti, Dimitrios Agas, Giorgio Santoni and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Pegi PavletićScuola di Scienze del Farmaco e dei Prodotti della Salute, Università di Camerino,, Camerino 62032, Italy.
Ana SemeanoDepartment of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States.
Hideaki YanoDepartment of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States.
Alessandro BonifaziMedicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health, 333 Cassell Drive, Baltimore, Maryland 21224, United States.ORCID 0000-0002-7306-0114
Gianfabio GiorgioniScuola di Scienze del Farmaco e dei Prodotti della Salute, Università di Camerino,, Camerino 62032, Italy.ORCID 0000-0002-9576-6580
Alessandro PiergentiliScuola di Scienze del Farmaco e dei Prodotti della Salute, Università di Camerino,, Camerino 62032, Italy.ORCID 0000-0001-6135-6826
Wilma QuagliaScuola di Scienze del Farmaco e dei Prodotti della Salute, Università di Camerino,, Camerino 62032, Italy.ORCID 0000-0002-7708-0200
Maria Giovanna SabbietiScuola di Bioscienze e Medicina Veterinaria, Università di Camerino, Via Gentile III da Varano, Camerino 62032, Italy.
Dimitrios AgasScuola di Bioscienze e Medicina Veterinaria, Università di Camerino, Via Gentile III da Varano, Camerino 62032, Italy.
Giorgio SantoniScuola di Scienze del Farmaco e dei Prodotti della Salute, Università di Camerino,, Camerino 62032, Italy.
Roberto PalliniInstitute of Neurosurgery, Scientific Hospitalization and Care Institute (IRCCS), Gemelli University Polyclinic Foundation, Rome 00168, Italy.
Lucia Ricci-VitianiDepartment of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome 00161, Italy.
Emanuela SabatoDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Mangiagalli 25, Milano 20133, Italy.
Giulio VistoliDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Mangiagalli 25, Milano 20133, Italy.ORCID 0000-0002-3939-5172
Fabio Del BelloScuola di Scienze del Farmaco e dei Prodotti della Salute, Università di Camerino,, Camerino 62032, Italy.ORCID 0000-0001-6538-6029
Università di Camerino · ITNortheastern University · USUniversity of Milan · ITIstituto Superiore di Sanità · ITNational Institutes of Health · USUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To better understand the role of dopamine D

Indexed as

Dopamine AntagonistsGlioblastomaReceptors, Dopamine D4beta-ArrestinsHumansLigandsTemozolomidebeta-ArrestinsDopamine AntagonistsLigandsReceptors, Dopamine D4Temozolomide

Identifiers

PMID36098685
PMCPMC9511495
OpenAlexW4295423299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.