Evidence map›Paper›PMID 36098684›Full record

RevieweLife2022

A global view of the aspiring physician-scientist.

Christopher S Williams, W Kimryn Rathmell, John M Carethers, Diane M Harper, Y M Dennis Lo, Peter J Ratcliffe, Mone Zaidi

Open access · goldAbstract readReview
In one paragraph

Review in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Transfiguration of Academic Departments of Medicine.The American journal of medicine · 2025
    Article
  14. Article
  15. 2024 Physician-Scientist Trainee Diversity Summit conference proceedings.Journal of clinical and translational science · 2025
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Christopher S WilliamsDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, United States.ORCID 0000-0002-1541-579X
W Kimryn RathmellDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, United States.ORCID 0000-0002-4984-0225
John M CarethersDepartment of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, United States.ORCID 0000-0003-2623-7332
Diane M HarperMichigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, United States.ORCID 0000-0001-7648-883X
Y M Dennis LoLi Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0001-8746-0293
Peter J RatcliffeThe Francis Crick Institute, London, United Kingdom.ORCID 0000-0002-2853-806X
Mone ZaidiCenter for Translational Medicine and Pharmacology, and Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID 0000-0001-5911-9522
University of Michigan · USChinese University of Hong Kong · HKIcahn School of Medicine at Mount Sinai · USThe Francis Crick Institute · GBUnited States Department of Veterans Affairs · USVanderbilt University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3M
Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
VOLT (Vanderbilt Oncology Training Program)T32CA217834 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Douglas B Johnson · 2018 to 2026
$2.7M
Vanderbilt Stimulating Access to Research in Residency (V-StARR)R38HL143619 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WEBBER, STEVEN A., WILLIAMS, CHRISTOPHER S. · 2018 to 2021
$1.3M
NCI NIH HHS K12 CA090625NCI NIH HHS T32 CA217834NHLBI NIH HHS R38 HL143619NIGMS NIH HHS T32 GM007347
6 · The paper itself

Abstract

Physician-scientists have epitomized the blending of deep, rigorous impactful curiosity with broad attention to human health for centuries. While we aspire to prepare all physicians with an appreciation for these skills, those who apply them to push the understanding of the boundaries of human physiology and disease, to advance treatments, and to increase our knowledge base in the arena of human health can fulfill an essential space for our society, economies, and overall well-being. Working arm in arm with basic and translational scientists as well as expert clinicians, as peers in both groups, this career additionally serves as a bridge to facilitate the pace and direction of research that ultimately impacts health. Globally, there are remarkable similarities in challenges in this career path, and in the approaches employed to overcome them. Herein, we review how different countries train physician-scientists and suggest strategies to further bolster this career path.

Indexed as

Biomedical ResearchPhysiciansCareer ChoiceHumansmedicinephysician-scientistScholarly Review Article in Medicinetraining

Identifiers

PMID36098684
PMCPMC9470153
OpenAlexW4295511710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.